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Abdulhakeem Funsho Ahmed1
Section:Research Paper, Product Type: Journal-Paper
Vol.9 ,
Issue.1 , pp.1-4, Jun-2022
Online published on Jun 30, 2022
Copyright © Abdulhakeem Funsho Ahmed . This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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IEEE Style Citation: Abdulhakeem Funsho Ahmed, “Effect of Shikoni on Phosphomonoesterase Activity of Mycobaterium Tuberculosis Protein Tyrosine Phosphotases (PTPs),” International Journal of Medical Science Research and Practice, Vol.9, Issue.1, pp.1-4, 2022.
MLA Style Citation: Abdulhakeem Funsho Ahmed "Effect of Shikoni on Phosphomonoesterase Activity of Mycobaterium Tuberculosis Protein Tyrosine Phosphotases (PTPs)." International Journal of Medical Science Research and Practice 9.1 (2022): 1-4.
APA Style Citation: Abdulhakeem Funsho Ahmed, (2022). Effect of Shikoni on Phosphomonoesterase Activity of Mycobaterium Tuberculosis Protein Tyrosine Phosphotases (PTPs). International Journal of Medical Science Research and Practice, 9(1), 1-4.
BibTex Style Citation:
@article{Ahmed_2022,
author = {Abdulhakeem Funsho Ahmed},
title = {Effect of Shikoni on Phosphomonoesterase Activity of Mycobaterium Tuberculosis Protein Tyrosine Phosphotases (PTPs)},
journal = {International Journal of Medical Science Research and Practice},
issue_date = {6 2022},
volume = {9},
Issue = {1},
month = {6},
year = {2022},
issn = {2347-2693},
pages = {1-4},
url = {https://www.isroset.org/journal/IJMSRP/full_paper_view.php?paper_id=2868},
publisher = {IJCSE, Indore, INDIA},
}
RIS Style Citation:
TY - JOUR
UR - https://www.isroset.org/journal/IJMSRP/full_paper_view.php?paper_id=2868
TI - Effect of Shikoni on Phosphomonoesterase Activity of Mycobaterium Tuberculosis Protein Tyrosine Phosphotases (PTPs)
T2 - International Journal of Medical Science Research and Practice
AU - Abdulhakeem Funsho Ahmed
PY - 2022
DA - 2022/06/30
PB - IJCSE, Indore, INDIA
SP - 1-4
IS - 1
VL - 9
SN - 2347-2693
ER -
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Abstract :
Several factors such as patient noncompliance and drug resistance affect the success rate of conventional treatments against tuberculosis and other pathogenic diseases; therefore there is need to improve the available therapeutic ways used in targeting tuberculosis treatment as well as design of new drugs that could act more rapidly on them. This research aimed to determine the effect of shikoni on phosphomonoesterase activity of mycobacterium tuberculosis using protein tyrosine phosphatases as enzyme inhibitor. Purified homogenous PTPs were obtained and shikoni phosphomonoesterase activity was determined by measuring the p-nitrophenol releases from the pNPP substrate. PTP acts as potential drug target which enables strategies to develop modern treatment regimen and regulate the levels of protein tyrosine phosphorylation under normal and pathological conditions.
Key-Words / Index Term :
Shikoni, Phosphatases activity, Mycobacterium Tuberculosis, Protein Tyrosine Phosphatases (PTPs)
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