Unravelling the Patterns of Antinuclear Antibodies (ANA) Indirect Immunofluorescence Assay (IFA): Insights and Implications

Pawan Kumar¹

Section:Research Paper, Product Type: Journal-Paper
Vol.11 , Issue.2 , pp.8-12, Jun-2024

Online published on Jun 30, 2024

Copyright © Pawan Kumar . This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
 

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Abstract :
The Antinuclear Antibodies (ANA) Indirect Immunofluorescence Assay (IFA) has long been a cornerstone for diagnosis and management of autoimmune diseases. This review aims to elucidate the diverse patterns observed in ANA IFA, exploring their clinical significance, diagnostic utility, and evolving implications in autoimmune diagnostics. We delve into the intricacies of interpreting ANA IFA patterns, emphasizing their correlation with specific autoimmune diseases and highlighting recent advancements in pattern recognition technologies. Furthermore, we discuss challenges, limitations, and future directions in ANA IFA interpretation, paving the way for enhanced precision and efficacy in autoimmune disease diagnosis.

Key-Words / Index Term :
ANA IFA, SLE, SSc, MCTD, RA, Sclerosis, CREST syndrome

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