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• Open Access   Article

  Alteration in Antioxidant Defense System and Oxidative Stress in blood for Non Alcoholic Fatty Liver Disease

  A.P. Thakkar, H.J. Shah, N.D. Patel, J.G. Shah

  Research Paper | Isroset-Journal (IJSRBS)

  Vol.4 , Issue.5 , pp.1-10, Oct-2017

  CrossRef-DOI:   https://doi.org/10.26438/ijsrbs/v4i5.110

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  Abstract
  Antioxidants neutralize free radicals or reactive oxygen species which cause oxidative stress. Oxidative stress is a major contributor in the pathogenesis of Non-alcoholic fatty liver disease (NAFLD). Present study is aimed to know level of antioxidant defense system and oxidative stress in controls and NAFLD participants. The cross-sectional study was carried out at tertiary centre of gastroenterologist unit at Anand. Experimental participants were divided into two groups: Control (n= 52, Age- 26.7±1.23 years, 39 M/ 13 F) and NAFLD (n= 48, Age- 41.71±1.71, 43 M/5 F). All participants underwent anthropometric assessment, clinical examination, biochemical parameters, antioxidant parameters and lipid peroxidation marker or oxidative stress marker (MDA- Malondialdehyde). Results of our study indicate significant increase in markers of metabolic syndrome (obesity, dyslipidaemia) and liver enzymes in NAFLD compared to controls. Total antioxidant activity (Gallic acid equivalent (GAE (p=0.0008)) and Trolox equivalent (TE (p<0.0001)) and antioxidant enzymes such as superoxide dismutase (SOD (p=0.0023)), Glutathione Peroxidase (GSHPx (p<0.0001)), Glutathione-s-transferase (GST (p<0.0001)) and Catalase (CAT (p<0.0001)) were significantly decreased in NAFLD compared to controls. Lipid peroxidation marker or oxidative stress marker (MDA) was significantly increased (p<0.0001) in NAFLD compared to controls. Our study concludes that NAFLD participants have increased oxidative stress and decreased antioxidant levels compared to controls. Study strongly indicates that antioxidant enzymes namely GST and CAT can be used as surrogate markers of oxidative stress for NAFLD participants.

  Key-Words / Index Term
  Anthropometric Assessment; Biochemical Parameters; Oxidative Stress Marker; Total Antioxidant Activity; Antioxidant Enzymes

  References
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  Citation
  A.P. Thakkar, H.J. Shah, N.D. Patel, J.G. Shah, "Alteration in Antioxidant Defense System and Oxidative Stress in blood for Non Alcoholic Fatty Liver Disease," International Journal of Scientific Research in Biological Sciences, Vol.4, Issue.5, pp.1-10, 2017

• Open Access   Article

  In silico subtractive hybridization of Nostoc azollae 0708 reveals that majority of proteins with hypothetical functions are unique in its proteome

  PV Parvati Sai Arun

  Research Paper | Isroset-Journal (IJSRBS)

  Vol.4 , Issue.5 , pp.11-13, Oct-2017

  CrossRef-DOI:   https://doi.org/10.26438/ijsrbs/v4i5.1113

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  Nostoc azollae 0708 is a cyanobacterium and live as an endo symbiont. The other Nostoc species such as Nostoc PCC 7107, Nostoc PCC 7120, Nostoc PCC 7524, Nostoc punctiforme PCC 73102 has different adaptation styles in their life style. Their adaptation in the environment range from hot fresh water pools to soil. Availability of the sequenced proteomes in public databases has led to the application of in silico subtractive hybridization method to predict the unique proteins of Nostoc azollae, which may be responsible for its endophytic behavior. Upon careful analysis, it is found that comparative proteome analysis of Nostoc azolle with other considered Nostoc species shows that the percentages of unique protein content ranges from 4.2% to 5.2% of which majority of proteins have hypothetical functions.

  Key-Words / Index Term
  Nostoc, In silico subtractive hybridization, endophytic, hypothetical proteins, unique proteins

  References
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  Citation
  PV Parvati Sai Arun, "In silico subtractive hybridization of Nostoc azollae 0708 reveals that majority of proteins with hypothetical functions are unique in its proteome," International Journal of Scientific Research in Biological Sciences, Vol.4, Issue.5, pp.11-13, 2017

• Open Access   Article

  Egg parasitism caused by Trichogramma spp. against maize stem borer, Chilo partellus.

  R.U. Aziz, S. Gaherwal

  Research Paper | Isroset-Journal (IJSRBS)

  Vol.4 , Issue.5 , pp.14-17, Oct-2017

  CrossRef-DOI:   https://doi.org/10.26438/ijsrbs/v4i5.1417

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  Abstract
  Present study was carried out to determine the numbers of egg batches and eggs per batch in the maize fields of selected sites of Indore. Moreover, discovery efficiency and parasitism efficiency was also determined. The result revealed that highest mean discovery efficiency rates of Trichogramma spp. was found from Mhow and was therefore having low parasitism per field and lowest mean discovery efficiency rate was recorded from Mangliya and was having high parasitism per field. There was generally a high variation in the numbers of egg batches and eggs per batch among the sites surveyed. The predominant parasitoid species was Trichogramma spp. This study showed that although egg parasitoid species diversity was higher, egg parasitism was considerably lower in selected sites of Indore.

  Key-Words / Index Term
  Trichogramma spp, discovery efficiency, egg parasitism. parasitism efficiency

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  Citation
  R.U. Aziz, S. Gaherwal, "Egg parasitism caused by Trichogramma spp. against maize stem borer, Chilo partellus.," International Journal of Scientific Research in Biological Sciences, Vol.4, Issue.5, pp.14-17, 2017

• Open Access   Article

  Enhancing Cloud and Big Data Systems for healthy Food and Nutrition Information Systems Practice: A Conceptual Study

  P.K. Paul, P.S. Aithal, A. Bhuimali

  Research Paper | Isroset-Journal (IJSRBS)

  Vol.4 , Issue.5 , pp.18-22, Oct-2017

  CrossRef-DOI:   https://doi.org/10.26438/ijsrbs/v4i5.1822

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  Abstract
  Cloud Computing is a kind of virtualization technology based on internet. In cloud computing, central remote server plays an important role for healthy data management and applications. It offers handsome efficiency in the field of Computing as well as Information Technology for providing centralized storage, money, processing, and bandwidth. Thus regardless of the size of the institute (i.e. big or small) there is no additional requirement for the establishment of own as well separate IT infrastructure for more and higher business units. Networking Technology and Internet Technology play a vital role in the establishment of cloud computing in different settings. Today it is treated as an emerging technology among the other applied Information Science & Technology. India is strong as well as developed in many senses with a good amount of educational institutes for diverse sectors and community. Cloud computing is applicable in a different field in the current scenario, such as Education, Public Administration, Business & Commerce, Health, and Medicine etc. Interestingly, cloud computing may be applicable in the field of Food and Nutrition. This is a conceptual paper deal with cloud computing related aspects which include benefits, advantages, challenges, and issues. Moreover, the paper also talks about cloud computing applications in different and diverse areas of Food Science, Nutrition and Dietetics. Further, the paper discusses some of the contemporary and future challenges to build Cloud Computing based Food Information Systems.

  Key-Words / Index Term
  Cloud Computing, Mobile Computing, Health Sciences, Food Science, Nutrition, Bio-Sciences.

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  Citation
  P.K. Paul, P.S. Aithal, A. Bhuimali, "Enhancing Cloud and Big Data Systems for healthy Food and Nutrition Information Systems Practice: A Conceptual Study," International Journal of Scientific Research in Biological Sciences, Vol.4, Issue.5, pp.18-22, 2017