Comparison and Prediction of toxicity parameters of principal Aflatoxins, antimicrobial compounds and Antifungal Drugs by pKCSM server

I.V. Ferrari¹ , M. Di Mario²

Section:Research Paper, Product Type: Journal-Paper
Vol.9 , Issue.1 , pp.48-52, Feb-2022

Online published on Feb 28, 2022

Copyright © I.V. Ferrari, M. Di Mario . This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
 

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Abstract :
The purpose of this short study is to estimate the main toxicity properties of main Aflatoxins, Antimicrobial bio- compounds and Antifungal Drugs by pKCSM server. Several tests are performed, for instance AMES toxicity; Max. tolerated dose (human) (log mg/kg/day in units); Oral Rat Acute Toxicity (LD50) (mol/kg in units) Oral Rat Chronic Toxicity (LOAEL); Log mg/kg_bw/day in units);Hepatotoxicity; Skin Sensitisation; Pyriformis toxicity (log µg/L)and Minnow toxicity (log mM in units).

Key-Words / Index Term :
pKCSM server, Aflatoxins, Antifungal Drugs

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