Fungicide Activity of New Complexes for Fungi Rhizoctonia solani, Fusarium solani and Macrophomina phaseolina

Abeer Mahmood¹ , Amira Al-Shaheen²

Section:Research Paper, Product Type: Journal-Paper
Vol.9 , Issue.3 , pp.39-44, Jun-2022

Online published on Jun 30, 2022

Copyright © Abeer Mahmood, Amira Al-Shaheen . This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
 

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Abstract :
This work includes the preparation and diagnosis of nine complexes which prepared interaction copper chlorides ,cobalt, nickel, and cobalt nitrate beside Schiff base salts obtain from N- dimethyl benzaldehyde with numerous amino acids like glycine and L-serine. we found that metal ions consistence to complexes as bidentate manner, condensation occurred via azomethine nitrogen with carboxylic oxygen atoms. Analytical data showed that all cobalt complexes1,2,3 having an octahedral geometries with the formula [Co(Bx)(H2O)2(NO3)] , Bx= (NaBg or NaBph), nickel complexes4,5,6,7 having tetrahedral geometries with the following formulas ; [Ni(Bz)(H2O)2]Cl ,where: Bz =(NaBg or NaBph or NaBs or Bt and [Co(By)(H2O)2]Cl ,where By =( NaBs or NaBt), while copper complexes8,9 having square planer geometries [Cu(Bz)(H2O)2]Cl, Moreover , Schiff base complexes elevated for antifungal activity in Vitro against three types of important pathogenic fungi namely :Fusarium solani,Macrophomina phaseolina and Rhizoctonia solani. All complexes gave significant inhibition against these pathogens especially4,8,9 complexes . The inhibition percentage of complex 9 with concentrate 100ppm against R solani,. F.solani was100%,99,3% and 75ppm had the same antifungal activity against R .solani and F.solani. 100% -93.9% respectively Moreover the percent inhibition increase to 64.7% with complex 8 at concentration 75ppm against M..phaseolina.

Key-Words / Index Term :
antifungal activity, Schiff base complexes

References :
[1] S.A.Ahmed,AL- A.J.Shaheen,I.J.Sallomi .”Inhibition Activity of Cobalt (II)Complexes Derived from Acid Hydrazide on Growth of Staphylococcus aureus and its Protein Contents”. Rafidain journal of science.. Vol. 27, No.4, pp.297-311,2018.
[2] W. Rehman, M.K.Baloch, B.Muhammad, A.Badshah, K.M.Khan. “Characteristic, spectral studies and in vitro antifungal activity of some Schiff bases and their organotin (IV) complexes”. Chinese science bulletin journal..Vol.49,No.2,pp.119-122,2004.
[3] R.Anjum, I.Khan., B.Ullah, M. Javed;”.Synthesis, spectral, thermal and antibacterial studies of Schiff base complexes derived from tyrosine and benzaldehyde.” journal of the chemical society of Pakistan. Vol.40.Issue.360-365. Apr 2018
[4] A.T.Shinde,B.T.Vhanale. “Synthesis, characterization, spectroscopic studies and biological evaluation of Schiff bases derived from 1-hydroxy-2-acetonapthanone.” Heliyon Journal.Vol. 5,Issue.11,pp:1-19 , 2019.
[5] A.A.Shanty, J.E.Philip, E.J.Sneha, M.R.Kurup, P. S.Balachandran, P.V.Mohanan. “Synthesis ,characterization and biological studies of Schiff bases derived from heterocyclicmoiety.”.Bioorganic.Chemistry journal.Vo. 70,pp.67-73, 2017
[6] A.Mumtaz ,T.Mahmud. “Structural investigation of some novel synthesized Schiff base Transition metal complexes derived from drug together with Antimicrobial study.” Pakistan journal of Pharmacy.Science. May.Vol.32No.3pp.963-967, 2019.
[7] A.A.Mohammad. “Synthesis and characterization of some new polydenate macrocyclic Schiff bases and their complexes with cobalt (II), nickel(II),copper(II) and zinc(II).”,Thesis, University of Mosul ,Iraq;2018.
[8] R.S.Bhaskar, A.S.Aswar. “Synthesis ,characterization and antimicrobial studies of novel ONO donor hydrazine Schiff base complexes with some divalent metal(II) ions.” Arabian Journal of chemistry,Vol.13No.8,pp.6559-6567,2020.
[9] M.W.Sabaa,.E.G. Araf .”Synthesis ,characterization and antimicrobial activity of Schiff bases modified chitosan-graft-poly(acrylonitrile).Apr2018.InternationalJournal of Biological.Macromolecules, Vol.109,No. 1,pp.1280-1291,2017.
[10] S.A.Matar, M.A.Aldamen,. “Synthesis Characterization, and antimicrobial activiy of Schiff bases derived from benzaldehydes and 3,3-diaminodipropylamine.” Arabian Journal of Chemistry,Vol.8,No.6,pp. 850-857,2015.
[11] Y. Xia, X. Liu, L. Zhang, J. Zhang, C. Li, N.Zhang, H. Xu1, Y. Li“A new Schiff base coordinated copper (II) compound induces apoptosis and inhibits tumor growth in gastric cancer: Cancer Cell International Vol.9, Issue.81,pp.2-11,2019.
[12] T.A. Kabanos and J.M. Tsangaris, Deprotonated and non-deprotonated complexes of N-(2-aminophenyl pyridine-2-carboxyamide and N-(3-aminophenyl) pyridine2-carboxyamide withCo(II), Ni(II), Cu(II) AND Pd(II)) Journal of Coordination ChemistryVol.13No.2,pp.89-103,1984.
[13] A.Gautami, S. Chandra.” Spectral and Biological Studies of Ni(II), Pd(II), Pt(IV) and Cu(II) Complexes with Novel Azamacrocyclic Ligand “.Asian Journal of Chemistry; Vol. 31, No. 2 ,pp396-402,2019.
[14]M. Tyagi,SH. Chandra, J.Akhtar,D. Chand.” Modern spectroscopic technique in the characterization of biosensitive macrocyclic Schiff base ligand and its complexes: Inhibitory activity against plantpathogenic fungi . Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy Vol. 118, Issue .24, pp1056–1061,2014.
[15]S. Shankarwar,B Nagolkar,V. Shelke,T. Chondhekar. Synthesis, spectral, thermal and antimicrobial studies of transition metal complexes of 14-membered tetraaza[N4] macrocyclic ligand Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, Vol,145, p. 188-193,2015.
[16] K .Singh, Barwa, M. S, Tyagi. P. “Synthesis, characterization and biological studies of Co (II), Ni (II), Cu (II) and Zn (II) complexes with bidentate Schiff bases derived by heterocyclic ketone”. Eurpean Journal Medicinal Chemistry. Vol.4,Issue.1,pp.147-153, 2006.
[17]M.V. Nai V., L.Siji.” Synthesis, spectral, thermal and antimicrobial studies of oxomolybdenum (V) and dioxomolybdenum (VI) complexes of Schiff base derived from 4-aminoantipyrine and 2, 4-dihydroxyacetophenone”.Journal of the Indian Chemical Society,Vol. 86,Issue.5,pp. 441-448. 2009.
[18]M.S. Alam, ,J.H.Choi,D.U Lee.” Synthesis of novel Schiff base analogues of 4-amino-1, 5-dimethyl-2-phenylpyrazol-3-one and their evaluation for antioxidant and anti-inflammatory activity”, Bioorganic & Medicinal Chemistry Jornal , Vol.20, Issue.13.pp.4103-4108,2012.
[19] B.B.Subudhi, G.Ghosh. “Synthesis and antibacterial activity of some heterocyclic derivatives of sulfanilamide”, The Bulletin of the Chemical Society of Ethiopia..; Vol.26,Issue.3,pp. 455-460,2012.
[20] A.Sahbaa,AL. Amira,J Sallomi.” Inhibition Activity of Cobalt (II) Complexes Derived from Acid Hydrazide on Growth of Staphylococcus aureus and its Protein Contents”, Rafidain Journal of Science, Vol. 27, Issue .4, pp 297-311,2018.
[21]F. Angelo , A. Paden , K.AmyL. Francesca,K .Hue G.Alysha,Z Johannes, G.Justin A.T.Mark .”Nontoxic Cobalt(III) Schiff Base Complexes with Broad-Spectrum Antifungal Activity”, Chemistry A European Journal .Vol.27Issue .7,pp.2021-2029, 2020
[22] E. J .Waheed,” Synthesis and Characterization of new Manganese(II), Cobalt(II), Cadmium(II) and Mercury(II) Complexes with ligand [N-(3-acetylphenylcarbamothioyl) -2-chloroacetamide] and their Antibacterial Studies”, J. Phys.: Conf. Ser.pp. 1234 .2019.
[23] A. M Abu-Dief, , I. M. A. Mohamed .”A review on versatile applications of transition metal complexes incorporating Schiff bases”. Beni-Suef University Journal of Basic and Applied Sciences.Vol. 4No.2,pp. 119–133,2015.
[24] M.AL.Rusul. A.ALSafaa, K.H.Malath . “Synthesis and characterization of new complexes of schiff bases derived from "sulfanilamide" with metal ions Hg+2, Zn+2 an evaluation their biological activity”. Kerbala journal of pharmaceutical sciences. Vol.4,No. 11,pp.299-313, 2016.
[25] A.T.Haj-husssein. “High-performance liquid chromatography of copper ,mercury ,nickel and bisdibenzyldithiocarbamate complexes .” Analytical Letters.,Vol.19,pp.11-12):1986.
[26] H.M.Afzal, , A.Fahad,, M.d, Tabish, R, Samira, F. Amir, . H.Mabood .”Copper(II) complexes as potential anticancer and Nonsteroidal anti-inflammatory agents: In vitro and in vivo studies,” Scientific Reports. ,Vol.9: 37-52.2019.
[27] A.Gaswell, H.Pressman. “Kinetic of transport of divalent cations across sarcoplasmic reticulum vesicles induced by inophores. “Biochemical and Biophysical research communication journal. Vol. 49Issue.1,pp.292-298,1972.
[28] E. Pontiki D.,Hadjipavloulitina, A.Chaviara. “Evaluation of anti-inflammatory and antioxidant activities of copper(II) Schiff mono-base and copper(II)Schiff base coordination compounds of dien with heterocyclic aldehydes and 2-amino methyliazole . “Journal of Enzyme inhibition and medicinal chemistry:Vol.23No.6,pp.1011-1017 2008.
[29 W.J.Geary. “The use of conductivity measurement in organic solvent for Characterization of coordination compounds.” Coord. Chem. Rev..Vol.7No.1,.pp.81-122,1971.
[30] J.N.Borase, Mahale,R.G. S.S.Rajput.” Design, Synthesis and biological evolution of heterocyclic methyl substituted pyridine Schiff base transition metal complexes.” International conference on research in education an science,The Eurasia proceeding of science ,technology, engineering $ mathematics, Turky,pp.151-161.2019.
[31] A.J.Shaheen .”Synthesis, Investigation and X-Ray Powder Diffraction (XRD) of Some Oxadiazole Complexes.” EPSTEM .Vol .6,No.2.pp, 151-161,2019
[32] J.Amira, R.A.Mustafa,A. Amal. “Synthesis and Characterization of some Metals(II) complexes with 2-(6- methoxy naphthalene-2-yl)Propionic acid(2- hydroxyl benzylidene) hydrazine.” IJERSTE,. Vol.7,Issue 4,pp.10-16, 2018.
[33] K.Nakamoto .’Infrared and Raman Spectra of Inorganic and Coordination Compounds.” 3rd ed, , New York .John Wiley and Sons, Chapter 1;p:154-322. 1997.
[34] I. Gamo.” Infrared Spectra of Water of Crystallization in Some Inorganic Chlorides and Sulfate”. BCSJ.,Vol.34No.6,pp.760-764,1960.
[35] S.Kumar, D.N. Dhar,P.N.Saxena.” Application of metal complexes of Schiff basees-“A review .JSIR. Vol.68No.3,pp.181-187 ,2009 .
[36] A.J. Al-Shaheen, S.A.Ahmed. “Preparation and physic chemical investigation Manganese(II) Complexes with hydrazone ligands.” Rafidain Journal of Science..Vol.28,No.2,pp.204-210 ,2019.
[37] R .Rajavel, M. S. Vadiva ,S. Antha. Synthesis ,Physical , Characterization and biological activity of some Schiff base of complexes .Journal of chemistry.Vol.5,No.3,pp.620-626, 2008
[38] S.S. Konstantinovic,. B.C. Radovanovc, S.P.Sovllj andS. Storojevis. “Antimicrobial activity of some isatin-3-thiosemcarbazone complexes “J. Serb. Chem. Soc. Vol.73,No.1,pp. 7-13,2008.
[39] N .El-wakiel, M. El-keiy,M. Gaber. “Synthesis, spectral, antitumor, antioxidant and antimicrobial studies on Cu(II),Ni(II) and Co(II) complexes of 4-[91HBenzoimidazol-2-ylimino)-methyl]-benzene-1,3-diol.”Asian social science journalVol.147No.5,pp.117-123, 2015.
[40] S.A. Shaker, , H .A .Mohammed, A. A. Salih.” “Preparation, Physico-Chemical and spectroscopic Investigation of thiacetazone and quinalizarin Complexes with Mn(II), Fe(II), Co(II), Ni(II) , Cu(II), Zn(II), Cd(II) and Pb(II)”.AJBAS. Vol.4,Issue.10,pp. 5178- 5183,2010.
[41] A. A. Mahmood. “The impact of biological control agents and chemicals on some plant pathogenic fungi”.2nd Scientific Con, Sci College ,Mosul University. Iraq, pp.262-275,2011.
[42] A. Abo-khadra, A. S, Afify A. Mohamed , R. S .Farag., A. Y. Enein. “Preparation, characterization and Antimicrobial activity pf Schiff base of (E)-N-(4-thiophen-2-ylmethyleneaminophenylsulfonyl) Acetamide metal complexes.”. Bio journal of science and technologyVol.6,Issue .1,pp.1-10, 2018.
[43] J.N. Borase1, R.G. Mahale, S.S. Rajput .”Synthesis, Antimicrobial and Antioxidant Activity of Heterocyclic Schiff Bases and Their Metal Complexes “. International Journal Science Research in Chemical Sciences Vol.7, Issue.4, pp.05-12, 2020.
[44] H. Chaudhry. “Synthesis, Characterization and Biological Aspects of O- and N-Donor Schiff Base Ligands and their Co(ll),Cu(ll),and Ni(ll) Complexe”. International Journal Science Research in Chemical Sciences ,Vol.7, Issue.2, pp.29-33, 2020.