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Sustainable Use of Plant Products In Ethnomedicine as a Promising Panacea to Effective Control of Trypanosomiasis: A Review

A. 1 , Aminu 2 , A. K.3 , Maigari 4 , I. H.5 , Hamza 6 , I. C.7 , Asongo 8 , K. I.9 , Nadada 10

Section:Review Paper, Product Type: Isroset-Journal
Vol.6 , Issue.2 , pp.13-17, Apr-2019


Online published on Apr 30, 2019


Copyright © A., Aminu, A. K., Maigari, I. H., Hamza, I. C., Asongo, K. I., Nadada . This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
 

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IEEE Style Citation: A., Aminu, A. K., Maigari, I. H., Hamza, I. C., Asongo, K. I., Nadada, “Sustainable Use of Plant Products In Ethnomedicine as a Promising Panacea to Effective Control of Trypanosomiasis: A Review,” International Journal of Scientific Research in Chemical Sciences, Vol.6, Issue.2, pp.13-17, 2019.

MLA Style Citation: A., Aminu, A. K., Maigari, I. H., Hamza, I. C., Asongo, K. I., Nadada "Sustainable Use of Plant Products In Ethnomedicine as a Promising Panacea to Effective Control of Trypanosomiasis: A Review." International Journal of Scientific Research in Chemical Sciences 6.2 (2019): 13-17.

APA Style Citation: A., Aminu, A. K., Maigari, I. H., Hamza, I. C., Asongo, K. I., Nadada, (2019). Sustainable Use of Plant Products In Ethnomedicine as a Promising Panacea to Effective Control of Trypanosomiasis: A Review. International Journal of Scientific Research in Chemical Sciences, 6(2), 13-17.

BibTex Style Citation:
@article{K._2019,
author = {A., Aminu, A. K., Maigari, I. H., Hamza, I. C., Asongo, K. I., Nadada},
title = {Sustainable Use of Plant Products In Ethnomedicine as a Promising Panacea to Effective Control of Trypanosomiasis: A Review},
journal = {International Journal of Scientific Research in Chemical Sciences},
issue_date = {4 2019},
volume = {6},
Issue = {2},
month = {4},
year = {2019},
issn = {2347-2693},
pages = {13-17},
url = {https://www.isroset.org/journal/IJSRCS/full_paper_view.php?paper_id=1306},
publisher = {IJCSE, Indore, INDIA},
}

RIS Style Citation:
TY - JOUR
UR - https://www.isroset.org/journal/IJSRCS/full_paper_view.php?paper_id=1306
TI - Sustainable Use of Plant Products In Ethnomedicine as a Promising Panacea to Effective Control of Trypanosomiasis: A Review
T2 - International Journal of Scientific Research in Chemical Sciences
AU - A., Aminu, A. K., Maigari, I. H., Hamza, I. C., Asongo, K. I., Nadada
PY - 2019
DA - 2019/04/30
PB - IJCSE, Indore, INDIA
SP - 13-17
IS - 2
VL - 6
SN - 2347-2693
ER -

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Abstract :
Trypanosomiasis is a vector-borne parasitic disease causing serious risksto the lives of about 60 million people and 48 million cattle globally. The current chemotherapy of trypanosomiasis relies on some of the drugs such as (suramin, pentamidine, melarsoprol, eflorinithine, arsobal and mel B) to mention but few which were developed more than 30 years ago. Others such as homidium, isometamidium and diminazene aceturate are used in animal infections. Each of these drugs has one or more of the following challenges: expensive, highly toxicity, parenteral administration and parasitic increasing resistance. Nigerian medicinal plants are known to contain a large variety of phytochemical components in the search for potential new drugs against the illness. Some of the plant extracts have been screened for anti-trypanosomes and they are classified based on their family and the specific part used against each parasite.

Key-Words / Index Term :
phytoconstituents, phytochemical, Trypanosomiasis,

References :
[1] D’Archivio, S.; Medina, M.; Cosson, A.; Chamond, N.; Rotureau, B.; Minoprio, P. “Genetic engineering of Trypanosoma (Dutonella) vivax and in vitro differentiation under axenic conditions”,PLoS Negl. Trop. Dis.,Vol, 5, e1461.2011.
[2] R.A., Joshua, Y., Magaji, Y.S., Kayit, “Isolation of human serum resistant Trypanozoon from cattle in Nigeria”,Tropenmedizin Parasitol, Vol. 13, pp. 201–202, 1983.
[3] O.M., Ayodele, F., Akinyemi, D., Charles, P., Kim, V.T., Michael, C.W., Susan, “A Longitudinal Survey of African Animal Trypanosomiasis in Domestic Cattle on the Jos Plateau, Nigeria: Prevalence, Distribution and Risk Factors", Parasites Vectors, Vol. 6, pp. 239, doi:10.1186/1756-3305-6-239, 2013.
[4] L., Airauhi, E.I., Unuigbe, O.D., Airauchi, “Human sleeping sickness (SS) in Nigeria: Knowledge, attitude and beliefs in a focus in the Abraka belt, Delta of Nigeri”, Afr. J. Clin. Exp. Microbiol., Vol. 2, pp. 6–9, 2001.
[5] H., Edeghere, E., Elhassan, J.C.A., Ukah, S., Sanda, M., Ikenga, G., Audu, “The scourge of human African trypanosomiasis in Abraka: possible control strategies”, Nig. Soc. Parasitol. Abst., Vol. 46, Issue, 43, 1998.
[6] B., Bauer, S., Amsler-Delafosse, I., Kabore, M., Kamunga, “Improvement of cattle productivity through rapid alleviation of African management practice in the Agropastoral zone of Yale, Burkina Faso Animal trypanosomosis by integrated disease”, Trop. Anim. Health Prod., Vol. 31, pp. 89–102, 1999.
[7] L., Griffin, W.E., Allonby, “The economic effect of trypanosomiasis in sheep and goats at a range research station in Kenya”, Trop. Anim. Health Prod., Vol. 11, pp. 127–132, 1979.
[8] K., Mulumba, “Socio Economic and Agricultural Factors in the Research and Control of Trypanosomiasis; PAAT Technical and Scientific Series4; FAO/WHO/IAEA/OAU: Rome, Italy, 3 January 2003.
[9] J.N., Abenga, I.A., Lawal, “Implicating roles of animal reservoir host in the resurgence of Gambian trypanosomiasis (Sleeping Sickiness)”, Afr. J. Biotechnol., Vol. 4, pp. 134–137, 2005.
[10] Fact Sheet N°259: Trypanosomiasis, Human African (Sleeping Sickness); WHO Media Centre: Geneva, Switzerland, 1 June 2013. Available online: http:www.who.int/mediacentre/ factsheets/fs259/en (accessed on 27 February 2014).
[11] P., Maser, A., Luscher, R. Kaminsky, “Drug transport and drug resistance in African trypanosomes”, Drug Resist. Updates, Vol. 6, pp. 281–290, 2003.
[12] N., Amaechi, “Toxicity of antiprotozoan drug diminazene aceturate in rats”, J. Sustain. Agric. Environ., Vol. 3, pp. 365–370, 2001.
[13] M., Kaiser, M.A., Bray, M., Cal, B.B., Trunz, E., Torreele, R., Brun, “Antitrypanosomal activity of Fexinidazole, a new oral Nitroimidazole drug candidate for treatment of sleeping sickness”, Antimicrob. Agents Chemother., Vol. 55, pp. 5602–5608, 2011.
[14] G., Ameenah, F.M., Mohamad, “African flora as potential sources of medicinal plants: Towards the chemotherapy of major parasitic and other infectious diseases—A review”, Jordan J. Biol. Sci., Vol. 6, pp. 77–84, 2013.
[15] A.W., Mbaya, U.I., Ibrahim, “In vivo and in vitro activities of medicinal plants on haemic and humoral trypanosomes: A review”, Int. J. Pharmacol., Vol. 7, 1–11, 2011.
[16] H.M., Malebo, W., Tanja, M., Cal, S.A.M., Swaleh, M.O., Omolo, A., Hassanali, U., Séquin, M., Hamburger, R., Brun, I.O., Ndiege, I. “Antiplasmodial, anti-trypanosomal, anti-leishmanial and cytotoxicity activity of selected Tanzanian medicinal plants”, Tanzania J. Health Res., Vol. 11, pp. 226–233, 2009.
[17] S., Hoet F., Opperdoes, R., Brun, J., Quetin-Leclercq, “Natural products active against African trypanosomes: A step towards new drugs”, Nat. Prod. Rep., Vol. 21, pp. 353–364, 2004.
[18] M. A., Ibrahim, A., Mohammed, M. B., Isah, A. B., Aliyu, “Anti-trypanosomal activity of African medicinal plants: A review update”, J. Ethnopharmacol., Vol. 154, pp. 26–54, 2014.
[19] T. J., Schmidt, S. A., Khalid, A. J., Romanha, T. M. A., Alves, M. W., Biavatti, R., Brun, F. B., Da Costa, S. L., De Castro, V. F., Ferreira, M. V. G., De Lacerda, The Potential of Secondary Metabolites from Plants as Drugs or Leads against Protozoan Neglected Diseases Part I”, Curr. Med. Chem., Vol. 19, pp. 2128–2175, 2012.
[20] T. J., Schmidt, S. A., Khalid, A. J., Romanha, T. M. A., Alves, M. W., Biavatti, R., Brun, F. B., Da Costa, S. L., De Castro, V. F., Ferreira, M. V. G., De Lacerda, The Potential of Secondary Metabolites from Plants as Drugs or Leads against Protozoan Neglected Diseases Part II”, Curr. Med. Chem., Vol. 19, pp. 2176–2228, 2012.
[21] I. V., Ogungbe, W. N., Setzer, “Comparative Molecular Docking of Antitrypanosomal Natural Products into Multiple Trypanosoma brucei Drug Targets”, Molecules, Vol. 14, pp. 1513–1536, 2009.
[22] D. J., Newmann, G. M., Cragg, “G.M. Natural products as sources of new drugs over the 30 years from 1981 to 2010”, J. Nat. Prod., Vol. 75, pp. 311–335, 2012.
[23] H. B., Matthews, G. W., Lucier, K. D., Fisher, “Medicinal herbs in the United States: Research needs”, Environ. Health Perspect., Vol. 107, 773–778, 1999.
[24] G. Y., Yeh, D. M., Eisenberg, T. J., Kaptchuk, R. S., Phillips, “Systematic review of herbs and dietary supplements for glycemic control in diabetes”, Diabetes Care, Vol. 26, 1277–1294, 2003.
[25] I. I., Hamdan, F. U., Afifi, “Studies on the in vitro and in vivo hypoglycemic activities of some medicinal plants used in treatment of diabetes in Jordanian traditional medicine”, J. Ethnopharmacol., Vol. 93, pp. 117–121, 2004.
[26] O., Rangasamy, G., Raoelison, F. E., Rakotoniriana, “Screening for anti-infective properties of several medicinal plants of the Mauritians flora” J. Ethnopharmacol., Vol. 109, pp. 331–337, 2007.
[27] M. F., Mahomoodally, A., Gurib-Fakim, A. H., Subratty, “Antimicrobial activities and phytochemical profiles of endemic medicinal plants of Mauritius”, Pharm. Biol., 2005, Vol. 43, pp. 237–242, 2005.
[28] M. F., Mahomoodally, A., Gurib-Fakim, A. H., Subratty, “Screening for alternative antibiotics: An investigation into the antimicrobial activities of medicinal food plants of Mauritius”, J. Food Sci., Vol. 75, pp. 173–177, 2010.
[29] L. G., Ranilla, Y. I., Kwon, E., Apostolidis, K., Shetty, “Phenolic compounds, antioxidant activity and in vitro inhibitory potential against key enzymes relevant for hyperglycemia and hypertension of commonly used medicinal plants, herbs and spices in Latin America”, Bioresour. Technol., Vol. 101, pp. 4676–4689, 2010.
[30] A., Ravi-Kumar, S., Ponnusamy, R., Ravindran, S., Zinjarde, S., Bhargava, “Evaluation of traditional Indian antidiabetic medicinal plants for human pancreatic amylase inhibitory effect in vitro”, Evid. Based Complement. Altern. Med., 2011, doi:10.1155/2011/515647.
[31] Administrative Map of Nigeria—Nations Outline Project. Available online: http://www.nationsonline.org (accessed on 2 February 2015).
[32] L. L., Lifongo, V. C., Simoben, F., Ntie-Kang, B. S., Babiaka, N. P., Judson, “A bioactivity versus ethnobotanical survey of medicinal plants from Nigeria, West Africa”, Nat. Prod. Bioprospect., Vol. 4, 1-19, 2014.
[33] R., Guadani, J., Patel, H., Prajapati, B., Mehta, S., Agrawal, “Peristrophe bicalculata—A review”, Pharmacogn. J., Vol. 2, pp. 39–45, 2010.
[34] M. A., Abdulazeez, A. B., Ibrahim, Z. Y., Edibo, J. O., Sidali, H. O., Idris, “Anti-trypanosomal effect of Peristrophe bicalyculata extract on Trypanosoma brucei brucei-infected rats”, Asian Pac. J.Trop. Biomed., Vol. 3, pp. 523–531, 2013.
[35] E. A., Awulu, S. J., Oniye, M. A., Adelanwa, “Phytochemical Screening and in vivo Antitrypanosomal Activity of Methanol Extracts of Peristrophe bicalyculata in Mice Infected with Trypanosomaevansi. Int. J. Sci. Technol., Vol. 3, pp. 34–39, 2013.
[36] A. J., Nok, S., Williams, “Allium sativum—Induced death of African Trypanosomes”, Parasitol. Res., Vol. 82, pp. 634–637, 1996.
[37] J. P., Alawa, G. E., Jokthan, K., Akut, “Ethnoveterinary medical practice for ruminants in the sub-humid zone of northern Nigeria”, Prev. Vet. Med., Vol. 54, pp. 79–90, 2002.
[38] S. E., Atawodi, T., Bulus, S., Ibrahim, D. A., Ameh, A. J., Nok, M., Mamman, M., Galadima, “In vitro trypanocidal effect of methanolic extract of some Nigerian savannah plants”, Afr. J. Biotechnol., Vol. 2, pp. 317–321, 2003.
[39] A. A., Adeiza, V. A., Maikai, F. B., Hassan, “Phytochemical screening and evaluation of some medicinal plants for their in vitro activities on Trypanosoma evansi”, J. Med. Plants Res., Vol. 3, pp. 315–318, 2009.
[40] E. O., Ogbadoyi, A. O., Abdulganiyu, T. Z., Adama, J. J., Okogun, “In vivo Trypanocidal activity of Annona senegalensis. Pers leaf extract against T. brucei brucei”, J. Ethnopharmacol., Vol. 112, pp. 85–89, 2007.
[41] N. J., Nwodo, R., Brun, P. O., Osadebe, In vitro and in vivo evaluation of the antitrypanosomal of fraction of Holarrhena Africana”, J. Ethnopharmacol., Vol. 113, pp. 556–559, 2007.
[42] J. O., Igoli, A. I., Gray, C. J., Clements, H. A., Mouad, “Anti-Trypanosomal Activity and cytotoxicity of some compounds and extracts from Nigerian Medicinal Plants. In Phytochemicals—Bioactivitiesand Impact on Health; Rasooli, I., Ed.; In Tech: Shanghai, China, pp. 375–388, 2011.
[43] R. E., Antia, J. O., Olayemi, O. O., Aina, E. O., Ajaiyeoba, In vitro and in vivo animal model antitrypanosomal evaluation of ten medicinal plant extracts from south west Nigeria”, Afr. J. Biotechnol., Vol. 8, pp. 1437–1440, 2009.
[44] A., Sofowora, Medicinal Plants and Traditional Medicines in Africa”, Spectrum Books LTD: Ibadan, Nigeria, pp. 289, 1990.
[45] A., Sofowora, “Research on Medicinal Plants and Traditional Medicine in Africa”, J. Altern. Complement. Med., Vol. 2, pp. 365–372, 1996.
[46] C. S., Onotu, U. B., Musa, A. O., Fajinmi, M. R., Mazadu, S. S., Shaida, “Physiochemical evaluation of ethanolic root extract of Carissa spinarum (Wild Karanda) on Trypanosoma brucei brucei (Federe Strain) infected mice. Int. J. Pharm. Sci. Invent., Vol. 2, pp. 18–26, 2013.
[47] S. E., Atawodi, “Comparative in vitro trypanocidal activities of petroleum ether, chloroform, methanol and aqueous extracts of some Nigerian savannah plants”, Afr. J. Biotechnol., Vol. 4, pp. 177–182, 2005.
[48] A. U., Wurochekke, N., Nuhu, G. O., Anyanwu, “Trypanocidal potential of Carrisa edulis in male wistar rats infected with T. congolense”, Am. J. Res. Commun., 2, 234–244, 2014.
[49] J., Omale J. B., Omajali, “Studies on some nutritional characteristics of the fruit and leaf of Saba florida (Benth) from Ibaji forest”, Int. J. Nutr. Metab.,Vol. 2, pp. 011–026, 2010.
[50] J., Omale, J. E., Joseph, “Comparative evaluation of trypanocidal activities of Cissus multistriata and Saba florida (benth) leaf extracts”, J. Biosci. Technol., Vol. 2, pp. 197-204, 2011.
[51] J. A., Abedo, O. A., Jonah, R. S., Abdullahi, M. R., Mazadu, H. Y., Idris, H., Muhammed, F. T., Shettima, S., Ombugadu, M., Daudu, J., Garba, “Evaluation of trypanosomal activity of Tapinanthus globiferus and Gongronema latifolium on Trypanosoma congolense”, Biosci. Res., Vol. 10, pp. 20–28, 2013.
[52] A., Abubakar, E. O., Ogbadoyi, J. I., Okogun, T. I., Gbodi, G. F., Ibikunle, “The identification of putative antitrypanosomal compounds in Tridax procumbens extracts” Int. J. Med. Aromat. Plants, Vol. 2, pp. 185–194, 2012.
[53] G. A., Cordell, M. L., Quinn-Beattie, N. R., Farnsworth, “The potential of alkaloids in drug discovery”, Phytother. Res., Vol. 15, pp. 183–205, 2001.
[54] D., Tasdemir, M., Kaiser, R., Brun, V., Yardley, T. J., Schmidt, F., Tosun, P., Ruedi, “Antitrypanosomal and antileishmanial activities of flavonoids and their analogues: In vitro, in vivo, structure-activity relationship, and quantitative structure-activity relationship studies”, Antimicrob. Agents Chemother., Vol. 50, pp. 1352–1364, 2006.
[55] M., Mamani-Matsuda, J., Rambert, D., Malvy, H., Lejoly-Boisseau, S., Daulouede, P., Thiolat, S., Coves, P., Courtois, P., Vincendeau, M. M., Djavad “Quercetin induces apoptosis of Trypanosoma brucei gambiense and diseases the proinflammatory response of human macrophages”, Antimicrob. Agent Chemother.,Vol. 48, pp. 924–929, 2004.
[56] A. C., Ene, S. E., Atawodi, Y. E. O., Apeh, “In vitro and in vivo antitrypanosomal effects of petroleum ether, chloroform and methanol extracts of Artemisia maritima Linn. Br. J. Pharm. Res., Vol. 4, pp. 751–758, 2014.
[57] N., Nwude, M. A., Ibrahim, “Plants used in traditional veterinary medical practice in Nigeria”, J. Vet. Pharmacol. Ther., Vol. 3, pp. 261–273, 1980.
[58] J. M., Dalziel, “Useful Plants of West Tropical Africa; Crown Agent for Overseas Governments: London, UK, pp. 462–463, 1937.
[59] F., Freiburghaus, R., Kaminsky, M. H. N., Nkuna, R., Brun, “Evaluation of African medicinal plants for their in vitro trypanocidal activity”, J. Ethnopharmacol., Vol. 55, pp. 1–11, 1996.
[60] S. E., Atawodi, J., Joseph-Idrisu, S. N., Uche, L. M. L., Yusufu, “Phytochemical and Antitrypanosomal Studies of Different Solvents Extracts of Boswellia dalzielii”, Int. J. Biol., Vol. 3, pp. 179-184, 2011.
[61] H. M., Burkill, Families A–D. In the Useful Plants of West Tropical Africa; Royal Botanic Garden, Kew Publishing: London, UK, Vol. 1, pp. 960, 1985.
[62] N. P., Igoli, A. I., Gray, C. J., Clements, J. O., Igoli, U., Nzekwe, R. K., Singla, “Scientific Investigation of Antitrypanosomal Activity of Crateva adansonii DC Leaves Extracts”, Indo Glob. J. Pharm. Sci., Vol. 2, pp. 226–229, 2012.
[63] N. E., Nweze, L. B., Fakae, I. U., Asuzu, “Trypanocidal activity of the ethanolic extract of Buchholzia coriacea seed”, Niger. Vet. J., Vol. 29, 1-6, 2009.
[64] O. S., Okere, U. D., Iliemene, “Proximate Analysis, Phytochemical Screening and Antitrypanocidal Potentials of Bucholzia coriacea in Trypanosoma brucei brucei-Infected Mice”, J. Pharm. Biol. Sci., Vol. 9, pp. 69–77, 2014.
[65] N. E., Nweze, B. M., Anene, I. U., Asuzu, “Investigation of the antitrypanosomal activity of Buchholzia coriacea seed extract against a field strain of Trypanosoma congolense. Afr. J. Tradit.Complement. Altern. Med., Vol. 8, pp. 175–180, 2011.
[66] J. O., Igoli, O. G., Ogaji, T. A., Tor-Anyiin, N. P., Igoli, “Traditional Medicine Practices Amongst the Igede people of Nigeria, Part II” Afr. J. Tradit. CAM, Vol. 2, pp. 134–152, 2005.
[67] T.O., Johnson, and B.P., Omoniwa, In Vivo Trypanocidal Activity of Ethanolic Crude Extract and Phytochemical Fractions of Garcinia kola Seeds”, Ann. Res. Rev. Biol., Vol. 4, pp. 212–222, 2014.

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