Assessment of Anti-diabetic Activity of Cassia Siamea Lam Leaves Ethanol Extract

B. Gawade¹ , M. Farooqui²

1. Dept. of Chemistry, Aandrao Dhonde Alias Babaji Mahavidyalaya, Kada (M.S.), India.
2. Dept. of Chemistry, Maulana Azad College of Arts, Science and Commerce, Aurangabad (M.S.), India.

Section:Research Paper, Product Type: Journal-Paper
Vol.7 , Issue.2 , pp.13-17, Apr-2020

Online published on Apr 30, 2020

Copyright © B. Gawade, M. Farooqui . This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
 

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Abstract :
The species of the genus Cassia has been reported for various pharmacological activities and their rich contents of phytochemicals use to treat health related disorders. The different parts of Cassia siamea Lam plant has been traditionally used as a medicine to treat diabetes mellitus related disorders. The assessment study aimed to investigate anti-diabetic activity of locally used medicinal plant Cassia siamea Lam leaves ethanol extract by porcine pancreatic α-amylase enzyme inhibition in vitro assay. A potent enzyme inhibitory activity was showed by the leaves of Cassia siamea Lam ethanol extract. The enzyme assay-guided leaves ethanol extract led to the inhibition activity of enzyme and has potent α-amylase inhibitor content of bioactive phytochemicals. This assessment study that describes the potency of Cassia siamea Lam medicinal plant leaves has been used an alternative medicine to treat disorders of diabetes mellitus.

Key-Words / Index Term :
Cassia siamea Lam, diabetes mellitus, α-amylase, phytochemicals, α-amylase inhibitor.

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