K-10 Montmorillonite Catalysed Solvent Free Synthesis of Coumarins via Pechmann Condensation

P.P. Kalbende¹ , N.B. Jadhav²

Section:Research Paper, Product Type: Journal-Paper
Vol.7 , Issue.5 , pp.15-21, Oct-2020

Online published on Oct 31, 2020

Copyright © P.P. Kalbende, N.B. Jadhav . This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
 

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Abstract :
An efficient solvent free one pot synthesis of coumarins by pechmann condensation of substituted phenols with ethyl acetoacetate using k-10 montmorillonite as a catalyst have been carried out. A plausible mechanism is proposed involving Michael addition resulting into the formation of coumarins. The reaction was refluxed at 1100C for 3-4 hrs on water bath. This one-pot synthesis was carried out on solid clay catalyst support which provides the products in good yields. Effect of molar ratio, amount of catalyst, reaction temperature and time on the yield of 4,7-dimethyl coumarin has been discussed. All the newly synthesized compounds were established from advanced spectroscopic data. The proposed method using the environmentally friendly recyclable catalyst k-10 montmorillonite offers the unique advantages of high yields, shorter reaction times, easy and quick isolation of the products and a one-pot green synthesis.

Key-Words / Index Term :
Solvent-free; coumarins; k-10 montmorrillonite; one-pot synthesis; pechmann condensation

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