Formation of Copper Metal Complexes with Medicinal Drugs in Ethanol Water Media

Ramesh Ware¹ , Kishore Koinkar² , Ashish Katariya³ , Hansaraj Joshi⁴ , Shailendrasingh Thakur⁵

Section:Research Paper, Product Type: Journal-Paper
Vol.11 , Issue.5 , pp.19-22, Oct-2024

Online published on Oct 31, 2024

Copyright © Ramesh Ware, Kishore Koinkar, Ashish Katariya, Hansaraj Joshi, Shailendrasingh Thakur . This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
 

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Abstract :
The stability constant of seven medicinal drugs with copper metal ion were investigate using pH metric titration technique in 20% (v/v) ethanol-water mixture at 300 K temperature and at an ionic strength of 0.1M NaClO4. {Metal to ligand ratio = 1:5 and 1:1} The method of Calvin and Bjerrum as adopted by Irving and Rossotti has been employed to determine proton- ligand pKa and metal-ligand stability constant logK values. It is observed that copper metal ion forms 1:1 and 1:2 complexes.

Key-Words / Index Term :
Stability Constant, copper metal, medicinal drugs, pH metry

References :
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