One-Pot Three Component Synthesis of some 8-Benzeloxy-5-{2-[N-(2-Chloro-Quinolin-3yl -Methelene)-Hydrazino]-Thiazole-4-yl}c-1H-Quinoline 2-Ones

Fahad T. Saleh¹ , Abdul Ahad² , Anis Ahmed³ , Syed Ummul Khair Asema⁴

Section:Research Paper, Product Type: Journal-Paper
Vol.11 , Issue.5 , pp.29-32, Oct-2024

Online published on Oct 31, 2024

Copyright © Fahad T. Saleh, Abdul Ahad, Anis Ahmed, Syed Ummul Khair Asema . This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
 

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Abstract :
Synthesis of a new series of 8-Benzeloxy-5-{2-[N-(2-chloro-quinolin-3ylmethelene)-hydrazino] is investigated in this work. One-pot multicomponent synthesis of -thiazole-4-yl-1H-quinoline-2-one was achieved by condensation of substituted 2. Chloroquinoline thiosemicarbazide, -3-carbaldehydes, and 8-benzyloxy-5-(2-bromo-acetyl)-1H-quinolin-2-one.

Key-Words / Index Term :
Multicomponent synthesis, quinoline, thiazole,maxium yields, room temperature conditions

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