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G.E. Sebiawu1 , S. Antwi-Akomeah2 , N.J. Mensah3 , D. Abana4
Section:Research Paper, Product Type: Journal-Paper
Vol.6 ,
Issue.5 , pp.15-23, May-2020
Online published on May 31, 2020
Copyright © G.E. Sebiawu, S. Antwi-Akomeah, N.J. Mensah, D. Abana . This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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IEEE Style Citation: G.E. Sebiawu, S. Antwi-Akomeah, N.J. Mensah, D. Abana, “Heavy Metal and Bacteriological Contamination of Herbal Medicines Sold Over the Counter in the Municipality of WA of the Upper West Region-Ghana.,” International Journal of Scientific Research in Multidisciplinary Studies , Vol.6, Issue.5, pp.15-23, 2020.
MLA Style Citation: G.E. Sebiawu, S. Antwi-Akomeah, N.J. Mensah, D. Abana "Heavy Metal and Bacteriological Contamination of Herbal Medicines Sold Over the Counter in the Municipality of WA of the Upper West Region-Ghana.." International Journal of Scientific Research in Multidisciplinary Studies 6.5 (2020): 15-23.
APA Style Citation: G.E. Sebiawu, S. Antwi-Akomeah, N.J. Mensah, D. Abana, (2020). Heavy Metal and Bacteriological Contamination of Herbal Medicines Sold Over the Counter in the Municipality of WA of the Upper West Region-Ghana.. International Journal of Scientific Research in Multidisciplinary Studies , 6(5), 15-23.
BibTex Style Citation:
@article{Sebiawu_2020,
author = {G.E. Sebiawu, S. Antwi-Akomeah, N.J. Mensah, D. Abana},
title = {Heavy Metal and Bacteriological Contamination of Herbal Medicines Sold Over the Counter in the Municipality of WA of the Upper West Region-Ghana.},
journal = {International Journal of Scientific Research in Multidisciplinary Studies },
issue_date = {5 2020},
volume = {6},
Issue = {5},
month = {5},
year = {2020},
issn = {2347-2693},
pages = {15-23},
url = {https://www.isroset.org/journal/IJSRMS/full_paper_view.php?paper_id=1889},
publisher = {IJCSE, Indore, INDIA},
}
RIS Style Citation:
TY - JOUR
UR - https://www.isroset.org/journal/IJSRMS/full_paper_view.php?paper_id=1889
TI - Heavy Metal and Bacteriological Contamination of Herbal Medicines Sold Over the Counter in the Municipality of WA of the Upper West Region-Ghana.
T2 - International Journal of Scientific Research in Multidisciplinary Studies
AU - G.E. Sebiawu, S. Antwi-Akomeah, N.J. Mensah, D. Abana
PY - 2020
DA - 2020/05/31
PB - IJCSE, Indore, INDIA
SP - 15-23
IS - 5
VL - 6
SN - 2347-2693
ER -
Abstract :
Analysed in the present study was heavy metal and microbial presence in fifteen (15) different herbal drugs sold at various herbal and chemical licensed shops across the Wa municipality of Ghana. Levels of the metals- Fe, Pb, Zn and Cu were analysed using Flame Atomic Absorption Spectrophotometer. Fe, Pb, Zn and Cu levels were below their respective WHO permissible limits. Fe emerged the most abundant metal, followed by Zn, Cu and Pb for all tested herbal drugs. Fe, Pb, Zn and Cu levels recorded respectively ranged from 1.530?0.007 to 6.774?0.012 ppm, 0.012?0.001 to 0.036?0.002 ppm, 0.935?0.008 to 3.612?0.006 ppm and 0.086?0.013 to 0.440?0.575 ppm. Microbiological analyses were performed by serial dilution and streak plating techniques. Total viable count was performed followed by isolation and enumeration of microbial species including Staphylococcus aureus, total coliforms and Salmonella, using appropriate selective media in each instance. Three (3) out of the fifteen (15) samples tested, representing 20% showed no microbial presence. The remaining twelve (12) samples representing 80% were found to contain microorganisms. They contained at most two (2) of the three (3) microbial species tested for their presence. Staphylococcus aureus emerged the most common microbial isolate being detected in six (6) out of the total samples tested (thus in 40% of samples). Total coliforms were detected in four (4) samples representing an estimated 27% whiles in three (3) of the samples tested, Salmonella spp. were detected (thus in 20% of samples).
Key-Words / Index Term :
Herbal medicines, Heavy metal contamination, Microbial contamination, Atomic absorption spectrophotometry, Wa Municipality
References :
[1] J.C. Tilburt,T.J. Kaptchuk.?Herbal medicine research and global health: An ethical analysis?. Bulletin of the World Health Organization, Vol. 86, pp. 594?599, 2008.
[2] World Health Organization. ?WHO traditional medicine strategy 2002?2005?. Geneva: Switzerland, pp. 1?59, 2002.
[3] Eisenberg D.M, R.B. Davis, S.L. Ettner, S. Appel, S. Wilkey, M.V. Rompay, R.C. Kessler. ?Trends in alternative medicine use in the United States (1990-1997): Results of a follow-up National survey?. Journal of American Medical Association, Vol. 280, pp. 1569-1575, 1998.
[4] H.T. Debas, R. Laxminarayan, S.E. Straus, (Eds.). ?Complementary and alternative medicine?, Chapter 69, pp. 1281. Washington, DC: World Bank, 2006.
[5] S.T. Odonkor, J. Osei, A.K Anim, C. Laar, M. Okyere. ?Microbiological quality of some herbal medicinal products sold in Accra,Ghana?. Elixir Pharmacy, Vol. 40, pp. 5499-5503, 2011.
[6] W. Busse. ?The significance of quality for efficacy and safety of herbal medicinal products?. Drug Information Journal, Vol. 34, pp. 15-23 2000.
[7] Traditional and Alternative Medicine Directorate. ?Strategy for formal institutionalization of plant medicine services, medical herbalism and complementary?. TM/CAM Strategy for 2010-2014. 2009.
[8] M.A. Nkansah, S.T. Hayford, L.S. Borquaye1, J. H. Ephraim?Heavy metal contents of some medicinal herbs from Kumasi, Ghana?. Cogent Environmental Science, Vol. 2: 1234660, pp. 1-8, 2016.
[9] D. Abba, H.I. Inabo, S.E. Yakubu, O.S. Olonitola. ?Contamination of herbal medicinal products marketed in Kaduna Metropolis with selected pathogenic bacteria?. African Journal of Traditional, Complementary and Alternative Medicines, Vol. 6, pp. 70-77, 2009.
[10] O.F. Kunle, H.O. Egharevba, P.O. Ahmadu. ?Standardization of herbal medicines- A review?. International Journal of Biodiversity and Conservation, Vol. 4, pp. 101-112, 2012.
[11] K. Annan, R.A. Dickson, I.K. Nooni, I.K. Amponsah.?The heavy metal contents of some selected medicinal plants sampled from different geographical locations?. Pharmacognosy Research, Vol. 5, pp. 103-108, 2013.
[12] D. Dei-Tutuwa, P. Amuna, M.A. Rahman. ?Rapid detection of microbial contamination in Ghanaian herbal medicines by PCR analysis?. Ghana Medical Journal, Vol. 48, No. 2, pp. 106-111, 2014.
[13] J. Soelberg, A. Asase, G. Akwetey, A.K. J?ger, ?Historical versus contemporary medicinal plant uses in Ghana.? Journal of Ethnopharmacology, Vol. 160, pp. 109-132, 2015.
[14] N.J. Mensah, S. Antwi-Akomeah, S. Akanlu, G.S. Etsey, S.M.B. Bieranye, D. Quarshie. ?Assessment of Cr, Cu, Fe, Ni and As contamination/pollution load indices in milled millet: evaluation of the impact of grinding plates in agro-food milling processes?. International Journal of Scientific Research in Multidisciplinary Studies, Vol. 6, Issue 1: pp. 21-29, 2020.
[15] Ghana Statistical Service, ?Population and housing census: Summary report of final results?. Sakoa Press Limited, Ghana, pp. 1-117, 2012.
[16] R.B. Voegborlo, S.E. Agorku, B. Buabeng-Acheampong, E. Zogli. ?Total mercury content of skin toning creams and the potential risk to the health of women in Ghana?. Journal of Science and Technology, Vol. 28, No. 1, pp. 88-96, 2008.
[17] N.J. Mensah, S. Antwi-Akomeah, S. Akanlu, S.M.B. Bieranye, E.G. Sebiawu, ?Residual levels of heavy metal contaminants in cattle hides singed with scrap tyre and firewood fuel sources: a comparative study in the Wa Municipality of Ghana?. American Journal of Environmental Science & Technology, Vol. 3, Issue 1: pp. 1-11, 2019.
[18] A.H. Uddin, R.S. Khalid, M. Alaama, A.M. Abdualkader, A. Kasmuri, S.A. Abbas. ?Comparative study of three digestion methods for elemental analysis in traditional medicine products using atomic absorption spectrometry?. J Anal Sci Technol, Vol. 7, Issue 6,pp. 1-7, 2016.
[19] M.M. Bumadian, H.H. Almansury, I.H. Bozakouk, Y.F. Lawgali, F.A. Bleiblo. ?Detection and enumeration of coliform bacteria in drinking water at hospital of Benghazi, Libya?. Journal of Experimental Biology and Agricultural Sciences, Vol. 1, Issue 6, pp. 436-440, 2013.
[20] D.P. Kateete, C.N. Kimani, F.A. Katabazi, ?Identification of Staphylococcus aureus: DNase and Mannitol salt agar improve the efficiency of the tube coagulase test?. Ann Clin Microbiol Antimicrob Vol.9, No.23,pp. 1-7, 2010.
[21] K.P. Brenner, C.C. Rankin, M. Sivaganesan, P.V. Scarpino. ?Comparison of the recoveries of Escherichia coli and total coliforms from drinking water by the MI agar method and the U.S. Environmental Protection Agency-approved membrane filter method?. Applied and Environmental Microbiology, Vol. 62, Issue 1, pp. 203-208, 1996.
[22] P. Feng, S.D. Weagant, M.A. Grant, W.Burkhardt. ?Enumeration of Escherichia coli and the coliform bacteria: InBacteriological Analytical Manual?, US Food and Drug Adminstration, 2007.
[23] A.Nair, T. Balasaravanan, S.V. Malik, V. Mohan, M. Kumar, J. Vergis, D.B. Rawool. ?Isolation and identification of Salmonella from diarrheagenic infants and young animals, sewage waste and fresh vegetables?. Veterinary world, Vol. 8, Issue 5, pp.669?673, 2015.
[24] U.A. Gilbert, A. Adekunle.?Evaluation of potentially toxic metal contamination of local medicinal plants and extracts sold in Ibadan, Nigeria?. Journal of Health & Pollution Vol. 7, No. 14, pp.23-29, 2017.
[25] World Health Organization (WHO).?WHO guidelines for assessing quality of herbal medicines with reference to contaminants and residues?. Geneva: Author. pp. 1-105, 2007.
[26] S. Ghiyasi, A. Karbassi, F. Moattar, S. Modabberi, M.B Sadough.?Origin and concentrations of heavy metals in agricultural land around aluminium industrial complex?. Journal of Food, Agriculture & Environment, Vol. 8, pp. 1237-1240, 2010.
[27] R.A. Street. ?Heavy metals in medicinal plant products - An African perspective?. South African Journal of Botany, Vol. 82, pp. 67-74, 2012.
[28] H. Sarma, S. Deka, H. Deka, R.R. Saikia. ?Accumulation of heavy metals in selected medicinal plants?. Reviews of Environmental Contaminationand Toxicology,Vol. 214, pp. 63-86, 2012.
[29] J. Denholm. ?Complementary medicine and heavy metal toxicity in Australia?. WebmedCentral, Vol. 1, pp. 1-6, 2010.
[30] U. Qelik, J. Oehlenschlager.?High contents of cadmium, lead, zinc and copper in popular fishery products sold in Turkish supermarkets?. Food Control, Vol. 18, pp. 258-261, 2007.
[31] M.M. Rao, A.G. KumarMeena. ?Detection of toxic heavy metals and pesticide residue in herbal plants which are commonly used in the herbal formulations?. Environmental Monitoring and Assessment, Vol. 181, pp. 267-271, 2011.
[32] K. Annan, A.I. Kojo, A. Cindy, A.N. Samuel, B.M. Tunkumgnen. ?Profile of heavy metals in some medicinal plants from Ghana commonly used as components of herbal formulations?. Pharmacognosy Research, Vol. 2, Issue 1, pp. 41-44, 2010.
[33] M.A. Nkansah, C.O.Amoako. ?Heavy metal content of some common spices available in markets in the Kumasi metropolis of Ghana?. American Journal ofScientific and Industrial Research, Vol. 1, pp. 158-163, 2010.
[34] K. Sarpong, G.O. Boateng. ?Hazardous metals concentrations in traditionally used unregistered herbal drugs sold at six selected Suburbs of Kumasi, Ashanti Region of Ghana?. Global Advanced Research Journal ofEducational Research and Reviews, Vol. 2, pp. 98-104, 2013.
[35] A. Maiga, D. Diallo, R. Bye,B.S. Paulsen..?Determination of some toxic and essential metal ionsin medicinal and edible plants from Mali?. Journal of Agricultural and Food Chemistry, Vol. 53, pp. 2316-2321, 2005.
[36] J. Baby, J.S. Raj, E.T. Biby, P. Sankarganesh, M.V. Jeevitha, S.U. Ajisha, S.S. Rajan. ?Toxic effect of heavymetals on aquatic environment?. International Journal ofBiological and Chemical Sciences, Vol. 4, pp. 939-952, 2010.
[37] T. Chionyedua, I. Onwordi, N. Agbo, I.A. Ogunwande.?Levels of potentially toxic metals in selected herbal medicines in Lagos,Nigeria?. Journal of NaturalSciences Research, Vol. 5, pp. 148-156, 2015.
[38] E.O. Salawu, A.A. Adeleke, O.O. Oyebowale, E.A. Ashamu, O.O Ishola, A.O. Afolabi, T.A. Adesanya. ?Prevention of renal toxicity from lead exposure by oral administration of Lycopersicon esculentum?. Journal of Toxicology and Environmental Health Sciences, Vol. 1, pp. 22-27, 2009.
[39] E. Obi, D.N. Akunyili, B. Ekpo, O.E. Orisakwe. ?Heavy metal hazards of Nigerian herbal remedies?. Sci Total Environ., Vol. 369, pp. 35-41, 2006.
[40] L.M. Bush, M.T. Perez. ?Staphylococcus aureus Infections?. MSD manual, Professional version, 2019.
[41] Minnesota Department of Health. ?Coliform Bacteria?, pp. 1-2, 2019.
[42] J. Seladi-Schulman, Y. Brazier. ?All you need to know about Salmonella?. Medical News Today, 2020.
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