Investigation of Phytochemical Properties of Cardiospermum halicacabum L. – An Anti-Rheumatic Plant

R. Murugan¹ , G. Kanimozhi² , B. Anandharaj³ , M. Sathya⁴

Section:Research Paper, Product Type: Journal-Paper
Vol.8 , Issue.2 , pp.31-34, Feb-2022

Online published on Feb 28, 2022

Copyright © R. Murugan, G. Kanimozhi, B. Anandharaj, M. Sathya . This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
 

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Abstract :
Plants are an essential source for treating a wide range of human and animal illnesses. As a result, current technologies must be used to scientifically confirm the biological activity of the selected plants. The medicinal plant Cardiospermum halicacabum is traditionally used in India and Southeast Asia. It possesses antibacterial, pain-relieving, antibiotic, anti-inflammatory, antioxidant, and anticancer effects, among others. Diabetes, arthritis, limb stiffness, rheumatism, muscle pain, earache, and fever are all popular uses. Due to the solubility of phytocompounds such as polyphenols and flavonoids in various solvents, the type of solvent and polarity have a significant impact on the antioxidant activity of extracts. The main aim of this present study was to screen phytochemical constituents from leaves of C. halicacabum. Shade dried plant materials were extracted with petroleum ether, chloroform and methanol by using Soxhlet apparatus until the decolorization of the solvents. Screening of phytochemicals was performed using standard methods and resulted in the detection of the presence alkaloids, flavonoids, phenols, tannins, carbohydrates, saponins, glycosides, protein, amino acid and anthroquinones. To assess their pharmacological potential and identify the structures of the bioactive chemicals responsible for their activities, more research with these plants is needed.

Key-Words / Index Term :
C. halicacabum, Medicinal plants, Phytochemicals, Alkaloids and Flavonoids

References :
[1] D. Hassawi, A. Kharma, “Antimicrobial activity of some medicinal plants against Candida albicans,” Journal of Biological Sciences, Vol.6, Issue.1, pp.109-114, 2006.
[2] R.A. Kumar, K. Sridevi, N.V. Kumar, S. Nanduri, S. Rajagopal, “Anticancer and immunostimulatory compounds from Andrographis paniculata”, Journal of Ethnopharmacology, Vol.92, Issue.2-3, pp.291-295, 2004.
[3] J. Parekh, D. Jadeja, S. Chanda, “Efficacy of aqueous and methanol extracts of some medicinal plants for potential antibacterial activity”, Turkish Journal of Biology, Vol.29, Issue.4, pp.203-210, 2006.
[4] V.N. Kadali, K.R. Kindangi, P.S. Rao, B.V. Sandeep, “Wonder Herbs Having Anti Asthmatic Activity Present in West Godavari District, Andhra Pradesh, India-A Mini Review”, Advances in Biology. Biotechnology and Genetics, Vol.3, Issue.(01), pp.01-06, 2016.
[5] R.Murugan, G. Kanimozhi, M. Sathya, B. Anandharaj, “Evaluation of preliminary phytochemical screening of five important medicinal plants in euphorbiaceae family”, International Journal of Botany Studies, Vol.7, Issue.1: pp.277-280, 2022.
[6] D. Shanmughanandhan, S. Ragupathy, S.G. Newmaster, S. Mohanasundaram, R. Sathishkumar, “Estimating herbal product authentication and adulteration in India using a vouchered, DNA-based biological reference material library”, Drug safety, Vol.39, Issue,12, pp.1211-1227, 2016.
[7] B. Anandharaj, M. Sathya, M. Maheshwari, B. Priyadharshini, V.P. Arun, R. Ramkumar, “Preliminary Phytochemical Screening of Natural Anti-dandruff plant Phyla nodiflora (L.) Greene (Lippia nodiflora)”, International Journal of Research Publication and Reviews, Vol.2, Issue.7, pp.1930-1932, 2021.
[8] J. Parekh, S. Chanda, “In vitro antimicrobial activity and phytochemical analysis of some Indian medicinal plants” Turkish Journal of Biology, Vol.31, Issue.1, pp.53-58, 2007.
[9] S.K. Paswan, S. Srivastava, C.V. Rao, “Wound healing activity of ethanolic extract of Selaginella bryopteris on rats” Pharmacognosy Journal, Vol.12, Issue.2, pp.335-341, 2020.
[10] S.N. Suresh, S. Rathishkumar, V. Rajeshwari, P. Sagadevan, S. Gayathri, D.V. Eswari, “Phytochemical analysis and antibacterial potential of Cardiospermum halicacabum Linn. (Sapindaceae)”, International Journal of Pharmacy and Life Sciences, Vol.3, Issue.12, pp.2209-2212, 2012.
[11] M.H. Huang, S.S. Huang, B.S. Wang, C.H. Wu, M.J. Sheu, W.C. Hou, S.S. Lin, G.J. Huang, “Antioxidant and anti-inflammatory properties of Cardiospermum halicacabum and its reference compounds ex vivo and in vivo”, Journal of Ethnopharmacology, Vol.133, Issue.2, pp.743-750, 2011.
[12] S.K. Karuppannan, R. Ramalingam, S.M. Khalith, M.J.H. Dowlath, G.D. Raiyaan, K.D. Arunachalam, “Characterization, antibacterial and photocatalytic evaluation of green synthesized copper oxide nanoparticles”, Biocatalysis and Agricultural Biotechnology, Vol.31, pp.101904, 2021.
[13] M.C. Jong, U. Ermuth, M. Augustin, “Plant-based ointments versus usual care in the management of chronic skin diseases: a comparative analysis on outcome and safety”, Complementary Therapies in Medicine, Vol.21, Issue.5, pp.453-459, 2013.
[14] M.A. Deshmukh, M.A. Theng, “Phytochemical screening, quantitative analysis of primary and secondary metabolites of Acacia arabica bark.” International Journal of Current Pharmaceutical Research, Vol.10, Issue.2, pp.35-37, 2018.
[15] J. Parekh, D. Jadeja, S. Chanda, “Efficacy of aqueous and methanol extracts of some medicinal plants for potential antibacterial activity”, Turkish Journal of Biology, Vol.29, Issue.4, pp.203-210, 2006.
[16] B. Vinoth, R. Manivasagaperumal, “Phytochemical analysis and antibacterial activity of Cardiospermum halicacabum Linn.”, The International Journal of Current Science and Technology, Vol.2, Issue.1, pp.9-12, 2013.
[17] T. Deepan, V. Alekhya, P. Saravanakumar, M.D. Dhanaraju, “Phytochemical and anti-microbial studies on the leaves extracts of Cardiospermum halicacabum Linn.”, Advances in Biological Research, Vol.6, Issue.1, pp.14-18, 2012.
[18] S.M. Kumar, V. Jiju, D. Chamundeeswari, “Investigation of phytoconstituents of Cardiospermum halicacabum and its efficacy as a potential anti-cancer drug candidate”, Journal of Drug Delivery and Therapeutics, Vol.9, Issue.4-s, pp.252-257, 2019.
[19] J. Preethi, L. Chitra, T. Palvannan, “Anti-gout effect of Cardiospermum halicacabum through antioxidant and xanthine oxidase inhibition property”, Journal of Pharmacognosy and Phytochemistry, Vol.7, Issue.2, pp.1300-1304, 2018.