Therapeutic Evaluation of Methanolic Leaf and Stem Extracts of Byrsocarpus Coccineus

Christiana Jesumirhewe¹ , Nzubechukwu Raphael² , Akibu Fajana³

1. Department of Pharmaceutical Microbiology, College of Pharmacy, Igbinedion University Okada Edo state, Nigeria.
2. Department of Public Health, Glasgow Caledonian University Scotland, United Kingdom.
3. Department of Pharmacognosy, College of Pharmacy, Igbinedion University Okada Edo state, Nigeria.

Section:Research Paper, Product Type: Journal-Paper
Vol.9 , Issue.1 , pp.40-44, Jan-2023

Online published on Jan 31, 2023

Copyright © Christiana Jesumirhewe, Raphael Nzubechukwu Raphael, Akibu Fajana . This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
 

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Abstract :
Byrsocarpus coccineus stem and leaves have been reported to have extensive ethno medicinal uses. The therapeutic evaluation of methanolic extracts obtained from the leaves and stem of Byrsocarpus coccineus was carried out to evaluate their antimicrobial potential and reported usefulness. The phytochemical screening of the powdered leaves and stem of Byrsocarpus coccineus were determined using previously described standard methods. The antimicrobial potency of the extracts on clinical isolates was determined using agar diffusion method. Phytochemical analysis of Byrsocarpus coccineus yielded important medicinal constituents which included glycosides, reducing sugars, tannins, alkaloids, saponins, phenols in both extracts. Result from the antimicrobial screening showed that the extract of the stem of Byrsocarpus coccineus had a significant inhibitory effect at 100mg/ml and 50mg/ml in comparison with the leaf extract. Gentamicin was used as a positive control. Results from this study validate the importance of Byrsocarpus coccineus especially stem extracts in the control of infections caused by microorganisms used in this study.

Key-Words / Index Term :
Byrsocarpus coccineus, Phytochemical screening, Antimicrobial activity, antimicrobial susceptibility, methanolic extracts

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