Immune response of goat (Capra hircus) against Fasciola hepatica

S. Solanki¹ , S. Gaherwal² , C. S. Shrivastava³

1. Department of Zoology, Govt. Holkar Science College, Indore, India.
2. Department of Zoology, Govt. Holkar Science College, Indore, India.
3. Department of Zoology, Govt. Holkar Science College, Indore, India.
4. Department of Zoology, Govt. Holkar Science College, Indore, India.

Correspondence should be addressed to: psgaherwal@yahoo.com.

Section:Research Paper, Product Type: Isroset-Journal
Vol.3 , Issue.6 , pp.11-15, Jun-2017

Online published on Jun 30, 2017

Copyright © S. Solanki, S. Gaherwal, C. S. Shrivastava . This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
 

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Abstract :
The immune response of goat against Fasciola hepatica was studied in the present investigation. Total 15 goats were examined for this study. The experimental animals were immunized with different somatic antigens. The immune response was observed by PCA and IgE response. The result showed that increased PCA response and increased IgE response found in immunized goats on 60th day post infection in compression to control goats. The maximum PCA reaction and IgE response were observed in goat vaccinated with larval somatic antigens and minimum PCA reaction and IgE response were observed in goat vaccinated with adult somatic antigens. Larval somatic antigens were observed more potent in providing protection as compared to Eggs and adult somatic antigens. The increased in PCA response and IgE response in infected and immunized goat compared to infected and non-immunized goat suggested the involvement of above studied parameters in immune response. This study also proves that larval somatic antigen of Fasciola hepatica was effective in imparting immunity in goat.

Key-Words / Index Term :
Fasciola hepatica, Capra hircus (Goat), Somatic Antigens, PCA, IgE response

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