Spectroscopic study of Enalapril Maleate and Hydrochlorothiazide

P. Bhattarai¹ , T. Katuwal²

Section:Research Paper, Product Type: Journal-Paper
Vol.9 , Issue.3 , pp.11-14, Jun-2021

Online published on Jun 30, 2021

Copyright © P. Bhattarai, T. Katuwal . This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
 

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Abstract :
In this work, Raman and Fourier Transform Infrared (FTIR) Spectroscopic techniques are utilized. For the study, Q-Pil 5 and Aquazide tablets were collected from the Banepa Hospital and Education Pvt. Ltd., Banepa, Kavre, which were the merchandise of Quest Pharmaceuticals P. Ltd., Birgunj, Nepal. The Q-Pil 5 and Aquazide contain enalapril maleate and hydrochlorothiazide, respectively, as active ingredients. Spectra of those samples are obtained with help of the EnSpectr Raport instrument (Raman) and FTIR instrument. The main peaks are obtained within the range 1000 -1700 cm-1 in Raman spectra and therefore the range 500 -1800 cm-1 in FTIR spectra. The functional groups corresponding to the main peaks are assigned. These functional groups observed in Raman and FTIR spectra were discovered to be present in the tablets` molecular structure. Hence, this study confirms the reliability of those products available within the market.

Key-Words / Index Term :
Raman spectroscopy, Fourier transform infrared spectroscopy, Enalapril Maleate, Hydrochlorothiazide

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