A Lindley Distribution Model for Intravenous Administration of Ghrelin Stimulates GH Secretion in Vagotomized Patients and Normal Subjects

M. Kaliraja¹ , K. Perarasan²

Section:Research Paper, Product Type: Isroset-Journal
Vol.6 , Issue.2 , pp.16-20, Apr-2019

CrossRef-DOI:   https://doi.org/10.26438/ijsrmss/v6i2.1620

Online published on Apr 30, 2019

Copyright © M. Kaliraja, K. Perarasan . This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
 

View this paper at   Google Scholar | DPI Digital Library

XML View     PDF Download

How to Cite this Paper

409 Views    483 Downloads    104 Downloads

Abstract :
A Lindley distribution is solitary approach to state the lifetime of a process or device. It can be employed in a broad range of meadows, together with engineering, medicine and biology. In this paper, we have utilized the two parameter lindley distribution to analyze the involvement of vagotomized nerve in gherlin-induced growth hormone (GH) secretion in humans. Further, the growth hormone responses to gherlin were compared in-between the vagotomized patients with gastrectomy and normal subjects with the help of lindley distribution.

Key-Words / Index Term :
Lindley distribution, Growth hormone, Parameters, Mean residual life function

References :
[1] D. V. Lindley, “Fiducial Distributions and Bayes. Journal of the Royal Statistical Society, Series B, Vol. 20, No. 1, 1958, pp. 102-107.
[2] D. V. Lindley, “Introduction to Probability and statistics From Bayesian Viewpoint,” Cambridge University Press, New York, 1965.
[3] E. G. Deniz and E. C. Ojeda, “The discreate lindley distribution-Properties and Applications,” Journal of Statistical Computation and Simulation, Vol. 81, No. 11, 2011, pp. 1405-1416.
[4] M. Sankaran, “The Discrete Poisson-Lindley distribution,” Biometrics, Vol. 26, No. 1, 1970. pp. 145-149.
[5] Sato M, Chihara K, Kita T, Kashio Y, Okimura Y, Kitajima N & Fujita T. Physiological role of somatostatin-mediated autofeedback regulation for growth hormone: importance of growth hormone in triggering somatostatin release during a trough period of pulsatile growth hormone release in conscious male rats. Neuroendocrinology 1989 50 139–151.
[6] Kojima M, Hosoda H, Date Y, Nakazato M, Matsuo H & Kangawa K. Ghrelin is a growth-hormone-releasing acylated peptide from stomach. Nature 1999 402 656–660.
[7] Howard AD, Feighner SD, Cully DF, Arena JP, Liberator PA, Rosenblum CI et al. A receptor in pituitary and hypothalamus that functions in growth hormone release. Science 1996 273 974–977.
[8] Takaya K, Ariyasu H, Kanamoto N, Iwakura H, Yoshimoto A, Harada M et al. Ghrelin strongly stimulates growth hormone release in humans. Journal of Clinical Endocrinology and Metabolism 2000 85 4908–4911.
[9] Rama Shanker, Shambhu Sharma, Ravi Shanker, A Two-Parameter Lindley Distribution for Modeling Waiting and Survival Times Data, Applied Mathematics, 2013, 4, 363-368
[10] Ryoko Takeno, Yasuhiko Okimura, Genzo Iguchi, Masahiko Kishimoto, Takumi Kudo, Kentaro Takahashi, Yutaka Takahashi, Hidesuke Kaji, Masakazu Ohno, Hajime Ikuta, Yoshikazu Kuroda, Tetsuji Obara, Hiroshi Hosoda, Kenji Kangawa and Kazuo Chihara, Intravenous administration of ghrelin stimulates growth hormone secretion in vagotomized patients as well as normal subjects European Journal of Endocrinology (2004) 151 447–450, ISSN 0804-4643.