Volume-6 , Issue-6 , Dec 2019, ISSN 2347-7520 (Online) Go Back
-
Open Access Article
Muthukkannan N., Balasaravanan T.
Research Paper | Journal-Paper (IJSRBS)
Vol.6 , Issue.6 , pp.1-12, Dec-2019
CrossRef-DOI: https://doi.org/10.26438/ijsrbs/v6i6.112
Abstract
Virgin Coconut Oil (VCO) was prepared from four coconut varieties viz., West Coast Tall, Arasampatti Tall, Deejay and Tiptur Tall. The Fresh-Dry methodology was optimized by three common variable parameters like temperature viz., 30±1ºC, 35±1ºC, 40±1º C, 45±1ºC, Drying intervals viz., 24hrs, 36hrs, 48 hrs, 60hrs and fruit maturity like 10, 11, 12 and 13 month old coconuts was taken to estimate the yielding efficiency of VCO .The yielding efficiencies are calculated from the four Coconut varieties by comparing the total percentage of Oil extracted from Soxhlet method. Among the four, the maximum yielding efficiency 95.33% was obtained in WCT Coconuts drying with 45º C. In the second process variable, where the maximum yield efficiency was showed that is 93.06% with 48 hrs drying. The third process variable showed the same maximum value of 93.06% as in second process variable by employing 12 month old coconuts The coconut varieties are taken in this research study, showed different yield composition of fatty acid profile especially the lauric acid percentage, which was registered maximum that is 51.20% at “WCT Coconuts” and in other coconut varieties such as AT, DJ and TT Coconuts were noted as 50.10%, 49.23% and 48.55% respectively.Key-Words / Index Term
VCO, yielding efficiency, Fresh-dry method, WCT, AT, DJ, TTReferences
[1] Bruce fife, “Health properties of coconut oil”, Agro Food Industry Hi-tech, Vol.24, Issue. 3, pp.5, 2013.
[2] K., Naveena, S. Rathod, G. Shukla, and K.J. Yogish, “Forecasting of coconut production in India: A suitable time series model”. International Journal of Agricultural Engineering, Vol.7, Issue.1,pp.190, 2014.
[3] K.S.V. Selvaraj, R. Rajendran, T. Saraladevi and H.P. Maheswarappa, “Evaluation of Coconut Hybrids Developed for High Nut and Copra”. Agricultural Research & Technology: Open Access Journal. Vol.5, Issue.4, pp.1, 2017.
[4] P. Appaiah, L. Sunil, P. K. Kumar and A. G. Krishna, “Physico-chemical characteristics and stability aspects of coconut water and kernel at different stages of maturity”, Journal of Food Science and Technology, Vol. 52, Issue.8, pp.5196, 2015a.
[5] P.L. Davis, S. Panneerselvam, B. Kannan, K.S. Subramanian, N.Shoba, and H.P.Maheswarappa, “Study on the Characteristics of Coconut Plantation in the Western Zone of Tamil Nadu - as a Source of Carbon Sink to Mitigate Climate Change”. International Journal of Current Microbiology and Applied Sciences, Vol. 6, Issue.12, pp.3480- 3489, 2017a.
[6] V.G. Chandrasekaran, “Collaborative research article on academic collaboration for coconut production estimate”, Indian Coconut Journal, Vol.7, pp. 26, 2013.
[7] Production and Marketing of coconut in India, “Marketing research and planning cell report from Nagpur”,pp.114, 2008a.
[8] S. Kappally, A. Shirwaikar and A.Shirwaikar, “Coconut Oil - A review of Potential Applications”. Hygeia journal for drugs and medicines, Vol.7, Issue.2, pp.34, 2015.
[9] M.S. Khan, Q.H. Lari and M.A. Khan, “Physico-Chemical and Pharmacological Prospective of Roghan-e-Narjeel (Coconut Oil)”. International Journal of Pharma Sciences and Research, Vol 6, pp 1268, 2015.
[10] J.A. Adeyanju, G.O. Ogunlakin, A.A. Adekunle, G.E. Alawode and O.S. Majekolagbe, “Optimization of oil extraction from coconut using response surface methodology”, Journal of Chemical and Pharmaceutical Research,vol.8, Issue.1,pp. 374-375,2016 a.
[11] M.O. Erin, Buenafe, T. Edward, Chainani, S. Ian Mitchelle, de Vera., I.K.D. Dimzon, E.G. Gonzales, “Standards for Essential Composition and Quality Factors of Commercial Virgin Coconut Oil and its Differentiation from RBD Coconut Oil and Copra Oil”. Philippine Journal of Science, Vol. 136, Issue. 2, pp.119-129,2007.
[12] S. Gandotra, J. Kour and V A.Waag, “Efficacy of Adjunctive Extra Virgin Coconut Oil Use in Moderate to Severe Alzheimer’s disease”. International Journal of School and Cognitive Psychology, Vol. 1, Issue. 2, pp.2, 2014.
[13] J.A. Adeyanju, G.O. Ogunlakin, A.A. Adekunle, G.E. Alawode and O.S. Majekolagbe, “Optimization of oil extraction from coconut using response surface methodology”, Journal of Chemical and Pharmaceutical Research,vol.8, Issue.1,pp. 374-375,2016 b.
[14] M.A. Hamid, M.R. Sarmidi, T.H. Mokhtar, W.R.W. Sulaiman and R.A. Aziz, “Innovative Integrated Wet Process for Virgin Coconut Oil Production”, Journal of Applied Sciences, Vol.11,pp.2467-2469, 2011.
[15] S.D.Nair, “Virgin is thy name and health is thy fame”. Indian Coconut Journal ,Vol.3, pp.36, 2012.
[16] Z.A. Amin, S. P. Koh, N.S.A. Hamid, C. P. Tan and K. Long, 2017.”New coating material for producing virgin coconut oil (VCO) microcapsules”, Food Research .Vol.1, Issue .1, pp.15, 2017.
[17] R. Gopalakrishnan, “Isolation, Characterization and evaluation of antioxidant and anticancer activity of polyphenol isolated from kernel and oil from coconut”, Indian Coconut Journal.Vol.7,pp.11, 2013a.
[18] J.A. Adeyanju, G.O. Ogunlakin, A.A. Adekunle, G.E. Alawode and O.S. Majekolagbe, “Optimization of oil extraction from coconut using response surface methodology”, Journal of Chemical and Pharmaceutical Research,vol.8, Issue.1,pp. 374-375,2016 c.
[19] T. S. T.Mansor, Y. B. Che Man, M. Shuhaimi, M. J.Abdul Afiq and F. K. M. KuNurul, “Physicochemical properties of virgin coconut oil extracted from different processing methods”. International Food Research Journal, Vol. 19, Issue. 3, pp. 835- 844, 2012 a.
[20] S.N. Raghavendra and K.S.M.S. Raghavarao, “Effect of different treatments for the destabilization of coconut milk emulsion”, Journal of Food Engineering, Vol. 97, pp.341–347, 2010.
[21] M.R. Manikantan, M. Arivalagan, A.C. Mathew and K.B.Hebbar, “Effect of processing parameters on recovery of hot process virgin coconut oil and co-products utilization”. Journal of Plantation Crops, Vol.43,Issue.2,pp.1, 2015.
[22] A.A.N.B. Mulawarman, M E. Arsana, I. W. Temaja, IBP. Sukadana, “Experimental study of the use of refrigeration systems as cooling and heating systems in the production process of the VCO”. Journal of Physics: Conf. Series .953.pp.2, 2018.
[23] T. Arumuganathan, K. Madhavan, and A.C. Mathew, “Development and performance evaluation of virgin coconut oil cooker”. Agricultural mechanization in Asia, Africa and Latin America, Vol.45, Issue. 1, pp.56-59. 2014.
[24] D.D.Bawalan and K.R.Chapman, “Virgin coconut oil production manual for micro- and village-scale processing”. In FAO Regional Office for Asia and the Pacific. Thammada Press Co. Ltd., Bangkok, Thailand.Chap.2, pp.21, 2006a.
[25] S.Naresh Kumar, “Variability in Coconut (Cocos.nucifera L.) Germplasm and Hybrids for Fatty Acid Profile of Oil”. Journal of Agric. Food Chemistry,Vol. 59, Issue .24, pp.13050–13058, 2011.
[26] R.Prapun, N.Cheetangdee, and S. Udomrati, “Characterization of virgin coconut oil (VCO) recovered by different techniques and fruit maturities”, International Food Research Journal. Vol.23 , Issue.5, pp. 2123, 2016a.
[27] P. Appaiah, L. Sunil, P. K. Kumar and A. G. Krishna, “Physico-chemical characteristics and stability aspects of coconut water and kernel at different stages of maturity”, Journal of Food Science and Technology, Vol. 52, Issue.8, pp.5196, 2015b.
[28] P.L. Davis, S. Panneerselvam, B. Kannan, K.S. Subramanian, N.Shoba, and H.P.Maheswarappa, “Study on the Characteristics of Coconut Plantation in the Western Zone of Tamil Nadu - as a Source of Carbon Sink to Mitigate Climate Change”. International Journal of Current Microbiology and Applied Sciences, Vol. 6, Issue.12, pp.3480- 3489, 2017b.
[29] A.G.Gopala Krishnan, G. Raj, A.S. Bhatnagar, P.K. Kumar and P.Chandrashekar, “Coconut Oil: Chemistry, Production and Its Applications -A Review”, Indian Coconut Journal, pp.15-18, 2016.
[30] J.K. Mannekote and S.V. Kailas, “Value addition to coconut - opportunities and challenges”. Indian Coconut Journal. pp.18-20, 2016.
[31] Production and Marketing of coconut in India, “Marketing research and planning cell report from Nagpur”,pp.114, 2008b.
[32] M. Abubakkar, Doctoral Thesis on “Economics of Coconut Cultivation in Theni District” submitted to Bharathidasan University, pp.139-140, 2014.
[33] K.S.V. Selvaraj, H.P.Maheswarappa, “Variability and Correlation in Coconut Germplasm for Morphological and Fruit Characters”, Advanced in Crop Science and Technology, Vol.4, Issue.3, pp.2, 2016a.
[34] S. Arulraj, “Experimental Results in Coconut”, Annual report (2005-2006) of All India Co-ordinated Research Project on Palms, Chap.3 (3.1):pp.13, 2006.
[35] H.P.Maheswarappa, V.Krishnakumar, Rajkumar, “Experimental Results in Coconut”, Annual report (2013-2014) of All India Co-ordinated Research Project on Palms,Chap.4 (4.1),pp.19, 2014.
[36] U. Tripura, P. Paramaguru, J. Suresh, N. Kumaravadivel, A. Subramanian and N.Shoba, “Performance of Indigenous and Exotic Coconut Germplasm for Yield and Nut Quality under Aliyarnagar Condition”.International Journal of Current Microbiology and Applied Sciences, Vol. 7, Issue.2, pp. 2613-2615, 2018a.
[37] R.V. Nair, P.M.Jacob, R.J. Thomas and M. Sasikala, “Development of varieties of coconut (Coconut nucifera L.) resistant / tolerant to root (wilt) disease”. Journal of Plantation Crops. (Supplement), Vol.32 ,pp.33-38, 2004a.
[38] K.S.V. Selvaraj, H.P.Maheswarappa, “Variability and Correlation in Coconut Germplasm for Morphological and Fruit Characters”, Advanced in Crop Science and Technology, Vol.4, Issue.3, pp.2, 2016b.
[39] J.A. Joshi, Doctoral thesis on “Investigations on invitro culture, genetic diversity and association analysis in coconut”. Submitted to the Tamil Nadu Agricultural University, pp.90, 2010.
[40] V.Niral, K. Devakumar, T.S. Umamaheswari, S. Naganeeswaran, R.V Nair, and B.A Jerard, “Morphological and molecular characterization of a large fruited unique coconut accession from Vaibhavwadi, Maharashtra, India”. Indian Journal of Genetics and Plant Breeding, Vol.73, Issue.2, pp.220-224, 2013a.
[41] M. Murali, “Economics of Good Coconut Farming”. Agro Look (International Crop Science Magazine). pp.14. 2013.
[42] S.John, “Deejay farm for the best hybrid seedlings”, Indian Coconut Journal, Vol.12, pp.31-33, 2012a.
[43] S.M. Yamuna and R. Ramya, “A Study of Coconut Cultivation and Marketing in Pollachi Taluk”. International Journal of Innovative Research in Management Studies, Vol. 1, Issue.2, pp.3, 2016.
[44] P.L. Davis, S. Panneerselvam, B. Kannan, K.S. Subramanian, N.Shoba, and H.P.Maheswarappa, “Study on the Characteristics of Coconut Plantation in the Western Zone of Tamil Nadu - as a Source of Carbon Sink to Mitigate Climate Change”. International Journal of Current Microbiology and Applied Sciences, Vol. 6, Issue.12, pp.3480- 3489, 2017c.
[45] T. K. Arumuganathan, A.C. Madhavan, Mathew and S. Padmanabhan, “Lipid profile of virgin coconut oil processed by different methods”. Journal of Plantation Crop, Vol. 39,Issue.1, pp.247, 2011.
[46] Y. Srivastava, A.D. Semwal and A. Majumdar, “Quantitative and qualitative analysis of bioactive components present in virgin coconut oil”, Journal of Cogent Food & Agriculture, Vol.2, pp.3, 2016.
[47] R. Prapun, N. Cheetangdee, and S. Udomrati, “Characterization of virgin coconut oil (VCO) recovered by different techniques and fruit maturities”, International Food Research Journal, Vol.23, Issue.5, pp.2118, 2016 b.
[48] R.Arlee, S.Suanphairochand P. Pakdeechanuan,. “Differences in chemical components and antioxidant-related substances in virgin coconut oil from coconut hybrids and their parents”, International Food Research Journal, Vol.20, Issue. 5, pp.2107, 2013.
[49] N.T. Oseni, W. Fernando, R. Coorey, I. Isona Gold and V.Jayasena, “Effect of extraction techniques on the quality of coconut oil”. African Journal of Food Science, Vol.11, Issue. 3, pp. 58-66, 2017.
[50] V.Niral, K. Devakumar, T.S. Umamaheswari, S. Naganeeswaran, R.V Nair, and B.A Jerard, “Morphological and molecular characterization of a large fruited unique coconut accession from Vaibhavwadi, Maharashtra, India”. Indian Journal of Genetics and Plant Breeding, Vol.73, Issue.2, pp.220-224, 2013b.
[51] R.V. Nair, P.M.Jacob, R.J. Thomas and M. Sasikala, “Development of varieties of coconut (Coconut nucifera L.) resistant / tolerant to root (wilt) disease”. Journal of Plantation Crops. (Supplement), Vol.32 ,pp.33-38, 2004b.
[52] U. Tripura, P. Paramaguru, J. Suresh, N. Kumaravadivel, A. Subramanian and N.Shoba, “Performance of Indigenous and Exotic Coconut Germplasm for Yield and Nut Quality under Aliyarnagar Condition”.International Journal of Current Microbiology and Applied Sciences, Vol. 7, Issue.2, pp. 2613-2615, 2018b.
[53] K.S.V. Selvaraj, H.P.Maheswarappa, “Variability and Correlation in Coconut Germplasm for Morphological and Fruit Characters”, Advanced in Crop Science and Technology, Vol.4, Issue.3, pp.2, 2016c.
[54] M. Murali, “Deejay Farms: Develops and Supplies coconut hybrid seedlings Based at Bangalore”. Agriculture and Industrial Survey Magazine, Vol.24, Issue. 9. pp.14-36, 2014.
[55] V. Niral, B. A.Jerard, K. Samsudeen, and R.V. Nair, “Evaluation of Coconut.Genetic Resources for Ball Copra Production”. National Conference on Horticulture Bio-Diversity for Livelihood, Economic Development and Health Care, UHS Bangalore,pp.30, 2010.
[56] G.V. Thomas, V. Krishnakumar and A.B. Augustine Jerard, “Improving productivity and profitability in coconut farming”. Proceedings in International Conference on Coconut Biodiversity for Prosperity, Central Plantation Crops Research Institute, Kasaragod, Kerala, India ,pp.39-61, 2010a.
[57] V.P.Dia, V.V.Garcia, R.C. Mabesa and E.M.T.Mendoza, “Comparative Physicochemical Characteristics of Virgin Coconut Oil Produced by Different Methods”. The Philippine Agricultural Scientist, Vol. 88, Issue.4, pp. 464, 2005.
[58] A.T.Quitain, T.Moriyoshi and M.Goto, “Coupling Microwave-Assisted Drying and Supercritical Carbon Dioxide Extraction for Coconut Oil Processing”. Chemical Engineering and Science, Vol.1,Issue.1, pp.13-16, 2013.
[59] C. Yalegama, M. Sovis and D.Dissanayake,” Effect of Antioxidant and Heat Treatment on the Free Fatty Acids Formation of Differently Processed Coconut Oil”. COCOS, Vol.21, pp.44, 2015.
[60] U. Patil and S. Benjakul, “Coconut Milk and Coconut Oil: Their Manufacture Associated with Protein Functionality”, Journal of Food Science, Vol.0, Issue.0 ,pp.1, 2018.
[61] R. Prapun, N. Cheetangdee, and S. Udomrati, “Characterization of virgin coconut oil (VCO) recovered by different techniques and fruit maturities”, International Food Research Journal, Vol.23, Issue.5, pp.2118, 2016 c.
[62] T. S. T.Mansor, Y. B. Che Man, M. Shuhaimi, M. J.Abdul Afiq and F. K. M. KuNurul, “Physicochemical properties of virgin coconut oil extracted from different processing methods”. International Food Research Journal, Vol. 19, Issue. 3, pp. 835- 844, 2012 b.
[63] Association of Official Agricultural Chemists (AOAC), Official method of analysis, Ed.20, 2017a.
[64] Z. Masyithah, “Parametric Study in Production of Virgin Coconut Oil by Fermentation Method”. Oriental Journal of Chemistry,Vol.33, Issue. 6, pp.3071-3076, 2017.
[65] N. Satheesh and N.B.L Prasad, “Production of Virgin Coconut Oil from Dry and Wet Methods of Induced Fermentation and its Characterization”, European Journal of Lipid Science and Technology, Vol.2, pp- 49, 2012.
[66] AOAC, Official method of analysis, “Oils and Fats”, Ed.20, Chap. 41; pp.6-14, 2016a.
[67] AOAC, Official method of analysis, “Oils and Fats”, Ed.20, Chap. 41; pp.6-14, 2016b.
[68] AOAC, Official method of analysis, “Oils and Fats”, Ed.20, Chap. 41; pp.6-14, 2016c.
[69] AOAC, Official method of analysis, “Oils and Fats”, Ed.20, Chap. 41; pp.6-14, 2016d.
[70] AOAC, Official method of analysis, “Oils and Fats”, Ed.20, Chap. 41; pp.6-14, 2016e.
[71] AOCS, Official method of analysis of American Oil Chemists Society. Preparation of methyl esters of fatty acids, USA. Method number Ce 2-66, 2000.
[72] SPSS version 16.0, “Polar Engineering and Consulting for Win wrap Series”, 2007.
[73] Y. Srivastava, A.D. Semwal, and G.K. Sharma, “Studies on storage stability of hot extracted (HEVCO) and cold extracted virgin coconut oil (CEVCO) in different flexible and rigid packaging system”. International Food Research Journal, Vol.20, Issue.4, pp.1973, 2013.
[74] P. Appaiah, L. Sunil, P. K. Kumar and A. G. Krishna, “Physico-chemical characteristics and stability aspects of coconut water and kernel at different stages of maturity”, Journal of Food Science and Technology, Vol. 52, Issue.8, pp.5196, 2015c.
[75] D.D.Bawalan and K.R.Chapman, “Virgin coconut oil production manual for micro- and village-scale processing”. In FAO Regional Office for Asia and the Pacific. Thammada Press Co. Ltd., Bangkok, Thailand.Chap.2, pp.21, 2006b.
[76] M.A Ali, “A study on coconut production and marketing in Tamil Nadu with special reference to Pollachi south block”, Thesis submitted to Bharathidasan University for the award of the Degree of Doctor of Philosophy in Economics, Chap.2.1, pp.52, 2012.
[77] S.John, “Deejay farm for the best hybrid seedlings”, Indian Coconut Journal, Vol.12, pp.31-33, 2012b.
[78] U. Tripura, P. Paramaguru, J. Suresh, N. Kumaravadivel, A. Subramanian and N.Shoba, “Performance of Indigenous and Exotic Coconut Germplasm for Yield and Nut Quality under Aliyarnagar Condition”.International Journal of Current Microbiology and Applied Sciences, Vol. 7, Issue.2, pp. 2613-2615, 2018c.
[79] K.S.V. Selvaraj, H.P.Maheswarappa, “Variability and Correlation in Coconut Germplasm for Morphological and Fruit Characters”, Advanced in Crop Science and Technology, Vol.4, Issue.3, pp.2, 2016d.
[80] G.V. Thomas, V. Krishnakumar and A.B. Augustine Jerard, “Improving productivity and profitability in coconut farming”. Proceedings in International Conference on Coconut Biodiversity for Prosperity, Central Plantation Crops Research Institute, Kasaragod, Kerala, India ,pp.39-61, 2010b.
[81] Association of Official Agricultural Chemists (AOAC), Official method of analysis, Ed.20, 2017b.
[82] N Satheesh, and N.B.L. Prasad, Optimization of parameters for fermentative production of virgin coconut oil by lactobacillus sp. Annals. Food science and Technology.Vol.14 ,Issue .2 ,pp. 314, 2013.
[83] R. Prapun, N. Cheetangdee, and S. Udomrati, “Characterization of virgin coconut oil (VCO) recovered by different techniques and fruit maturities”, International Food Research Journal, Vol.23, Issue.5, pp.2118, 2016 d.
[84] T.Arumuganathan, K. Madhavan, A.C. Mathew and P. Sugada, Lipid profile of virgin coconut oil processed by different methods. Journal of Plantation Crops Vol.39, Issue.1, pp.247-251, 2011.
[85] S.F. Baltasar, “Coconut oil extraction employing the dry processing technology”. Philippines Journal of Coconut Studies, Vol.2, Issue.4, pp.40-42, 1977.
[86] P.J. Ferrer, V.F. Quilinguen, J. Rosario and L.D. Pestano, “Process Design of Virgin Coconut Oil (VCO) Production Using Low-Pressure Oil Extraction”. MATEC Web of Conferences,Vol.156, pp.3, 2018.
[87] K.D.P.P.Gunathilake, “Processing technologies for virgin coconut oil and coconut based Confectionaries and beverages”. Proceedings of International Coconut Summit at Kochi, pp.4, 2007.
[88] N.Kapila, Seneviratne, D. Chamil, Hapuarachchi, S. Ekanayake, “Comparison of the phenolic-dependent antioxidant properties of coconut oil extracted under cold and hot conditions”, Food Chemistry,Vol.114, pp. 1444–1449, 2009.
[89] N.A.A. Ghani, A.A. Channip, P.C.H. Hwa, F.Jaafar, H.M. Yasin and A.Usman, “Physicochemical properties, antioxidant capacities, and metal contents of virgin coconut oil produced by wet and dry processes”, Food Science and Nutrition, Vol.6,pp. 1298–1306, 2018.
[90] R. Prapun, N. Cheetangdee, and S. Udomrati, “Characterization of virgin coconut oil (VCO) recovered by different techniques and fruit maturities”, International Food Research Journal, Vol.23, Issue.5, pp.2118, 2016e.
[91] E. Choe and D.B.Min, “Comprehensive Reviews in Food Science and Food Safety Mechanisms and Factors for Edible Oil Oxidation”. Comp. Rev. Food Science and Food Safety, Vol.5,pp.169-186, 2006.
[92] S.N. Raghavendra and K.S.M.S Raghavarao, “Aqueous extraction and enzymatic destabilization of coconut milk emulsions”, Journal of American Oil Chemistry Society, Vol.88,Issue.4, pp.481-487, 2011.
[93] P. Singh, Fatty Acid Compositional Analysis of Different Edible Oils and Fats in the kairwara, Alwar (Rajasthan),International Journal of Scientific Research in Chemical Sciences,Vol.5,Issue.4,pp.12, 2018.
[94] P.K Ghosh, P. Bhattacharjee, S.Mitra and M. Sarkar, “Physicochemical and Phytochemical Analyses of Copra and Oil of Cocos nucifera L. (West Coast Tall Variety)”, International Journal of Food Science. Article ID 310852, pp.4, 2014.
[95] A.G. GopalaKrishnan, G. Raj, A.S.Bhatnagar, P.K. Kumar and P. Chandrashekar, Coconut Oil: Chemistry, Production and Its Applications -A Review. Indian Coconut Journal, pp.15-18, 2016a.
[96] D.D.Bawalan and K.R.Chapman, “Virgin coconut oil production manual for micro- and village-scale processing”. In FAO Regional Office for Asia and the Pacific. Thammada Press Co. Ltd., Bangkok, Thailand.Chap.2, pp.21, 2006c.
[97] A.G. GopalaKrishnan, G. Raj, A.S.Bhatnagar, P.K. Kumar and P. Chandrashekar, Coconut Oil: Chemistry, Production and Its Applications -A Review. Indian Coconut Journal, pp.15-18, 2016b.
[98] R. Prapun, N. Cheetangdee, and S. Udomrati, “Characterization of virgin coconut oil (VCO) recovered by different techniques and fruit maturities”, International Food Research Journal, Vol.23, Issue.5, pp.2118, 2016e.
[99] Y. Viduranga, Waisundara, C.O. Perera, P.J. Barlow, “Effect of different pre-treatments of fresh coconut kernels on some of the quality attributes of the coconut milk extracted”. Journal of Food Chemistry, Vol.101, pp. 776, 2007.
Citation
Muthukkannan N., Balasaravanan T. , "Optimization of Process Variables for the Production of Virgin Coconut Oil from Selected Cocos Nucifera Varieties under Fresh-Dry Method," International Journal of Scientific Research in Biological Sciences, Vol.6, Issue.6, pp.1-12, 2019 -
Open Access Article
Dawa ul Misk Motadil Sada a Classical Unani Formulation for Khafaqān (Palpitation)
Fouzia Bashir, Jamal Akhtar, Nighat Anjum, Shah Alam, Asim Ali Khan
Research Paper | Journal-Paper (IJSRBS)
Vol.6 , Issue.6 , pp.13-22, Dec-2019
CrossRef-DOI: https://doi.org/10.26438/ijsrbs/v6i6.1322
Abstract
Unani System of medicine is one among the oldest systems that prevails till date with its efficient drugs derived from animal, plant and mineral resources. Over 2400 years ago, the father of medicine Hippocrates practiced it; however His medicine included a great deal of ancient Egyptian medicine as well as important components of the ancient Mesopotamian traditions. In modern medicine, Palpitation is described as an uncomfortable awareness of one’s own heartbeat and is a clinical entity with varied etiology ranging from benign causes to serious arrhythmias. In Unani system of medicine, the modern equivalent term for palpitation is Khafaqān. A large number of drugs, single and compound formulations, have been mentioned in the context of the treatment of Khafaqān. Dawa ul Misk Motadil Sada is one of the most reputed poly pharmaceutical preparations of Unani system of Medicine used in Khafaqān, as cardiac tonic in arrhythmia and as general tonic.Key-Words / Index Term
Dawa ul Misk Motadil Sada, Palpitation, Unani MedicineReferences
[1] Anonymous, “Physicochemical standards of Unani formulations”, Central Council for Research of Unani Medicine, Dept. of AYUSH, New Delhi, India, Part 4, pp. 5, 2006.
[2] Anonymous, “National Formulary of Unani Medicine”, Central Council for Research of Unani Medicine, Dept. of AYUSH, New Delhi, India, Vol. I. pp. 90, 2008.
[3] Anonymous, “The Unani Pharmacopoiea of India”. CCRUM, Dept. of AYUSH, New Delhi, India, Part 1, Vol I. pp. 56, 57, 76, 77, 88, 89, YNM.
[4] H. M. A. Arzani, “Qarabadeen Quadri” Munshi Nawal Kishore, Kanpur, India, pp. 453, 1268.
[5] Anonymous, “Qarabadeen Sarkari”, Ministry of Health & Family welfare, New Delhi, India, pp.181-182, YNM.
[6] Anonymous, “Qarabadeen Azam wa Akmal”, Central Council for Research of Unani Medicine, Dept. of AYUSH, New Delhi, India, pp. 472, YNM.
[7] H. A Hameed, H. M Said, “Hamdard Pharmacopoeia of Eastern medicine”, Sri Satguru publications, Delhi, pp. 274-275, 1997.
[8] G.A. Ali, “Ilaj ul Gurba”, Idarah Kitab us shifa, New Delhi, pp.153-157.
[9] T. Ahmad, M. Tariq, J. I. Siddiqui, M.W. Ahmed, M. H. Kazmi “A Review on Operculina turpethum- A Potent Herb of Unani System of Medicine”, Journal of Pharmacognosy and Phytochemistry, Part 6, Vol. I, pp. 23-26, 2017.
[10] M A. Hakim, “Bustanul Mufredat”, Idara Kitabus Shifa, New Delhi, India, pp. 60, 90, 145, 180, 209, 235-36, 249, 266, 316, 470, 558, 2002.
[11] H. M. A. Arzani, “Tibb e Akbar”, Idara Kitab Us Shifa, New Delhi, India, pp. 614-617.
[12] H. M. A. Arzani, “Meezan ul Tib” (Urdu), Edi. I pp.178-81, 756.
[13] H. M. Kabeeruddin, “Ikseer e Azam”, (Urdu translation), Ejaz Publishing House, New Delhi, India, Vol. 2, pp.1430-1447.
[14] M. A. Khan, “Qarabadeen-e-Azam” Aijaz Publishing House, New Delhi, India, pp. 576, 1957.
[15] I. A. Majusi, “Kamil us Sana”, (Urdu), Idarah Kitab Us Shifa, New Delhi, Vol 2, pp. 277.
[16] H. M. Kabeeruddin, “Bayaz e Kabeer”, Hikmat Book Depot, Hyderabad, India, Vol. 1, pp. 137, YNM.
[17] B. K. Tiwari, R. L. Khosha, “Evaluation of the Hepato-protective and antioxidant effect of Berberis asiatica against experimentally induced liver injury in rats”, International Journal of Pharmacy and Pharmaceutical Sciences, Part. 2, Vol.1, 2010.
[18] A.H. Gilani, K.H. Janbaz, “Preventive and curative effects of Berberis aristata fruit extract on paracetamol- and CCl4- induced hepatotoxicity”, Phytotherapy Res, Vol. 9, pp. 489-94, 1995.
[19] K.H. Janbaz, A. H. Gilani, “Studies on preventive and curative effects of berberine on chemical-induced hepatotoxicity in rodents”, Fitoterapia, Vol. 71, pp. 25-33, 2000.
[20] A.H. Gilani, K.H. Janbaz, N. Aziz, M. J. U. Herzig, M.M. Kazmi, M. I. Choudhary, J.W. Herzig, “Possible mechanism of selective inotropic activity of the n-butanolic fraction from Berberis aristata fruit - distinguishing hype from hope”, General Pharmacology, Vol. 33, Part 5, pp. 407-414, 1999.
[21] M.S. Akhtar, M.S. Sajid, M. Ahmad, “Hypoglycemic effect of Berberis aristata root, its aqueous and methanolic extract in normal and alloxan induced diabetic rabbits”, Pharmacology online (Italy), Vol. 2, pp. 845-856, 2008.
[22] B.C. Semwal, J. Gupta, S. Singh, Y. Kumar, M. Giri, “Antihyperglycemic activity of root of Berberis aristata d.c. in alloxan induced diabetic rat”, International Journal of green pharmacy Issue. 3, pp. 259-63, 2009.
[23] A. Rehan, S. Swayam, Prakash, M. Rakesh, S. M. Rajendran, K.R. Arya, A. K. Srivastava, “Mild Antihyperglycemic activity in Eclipta alba, Berberis aristata, Betula utilis, Cedrus deodara, Myristica fragrans and Terminalia chebula”, Indian Journal of Science and Technology ,Vol.1, Issue 5, pp.1-6, 2008.
[24] J. K. Gupta, P. Mishra, A. Rani, P. Mazumder, “Blood Glucose Lowering Potential of Stem Bark of Berberis aristata Dc in Alloxan-Induced Diabetic Rats”, Iranian Journal of Pharmacology & Therapeutics, Vol. 9, Issue.1, pp. 21-24, 2010.
[25] S. Kamal, N. S. Chauhan, B. C. Semwal, R. Badhe, K. Divakar, “Antidiabetic activity of stem bark of Berberis aristata D.C. (Berberdiaceae) in alloxan induced diabetic rats”, International Journal of Pharmacology , 2008.
[26] J. Singh, P. Kakkar, “Anti hyperglycemic and antioxidant effect of Berberis aristata root extract and its role in regulating carbohydrate metabolism in diabetic rats”. Journal of Ethnopharmacology; Vol.123, Issue 1, pp.22-6, 2009.
[27] D. Sanjita, B. S. Priya, Cytotoxic Activity of Methanolic Extract of Berberis aristata DC on Colon Cancer”, Global Journal of Pharmacology, Vol. 3, Issue 3, pp.137-140, 2009.
[28] M. M. Papiya, D. Saumya, D. Sanjita, K. D. Manas, “Cytotoxic Activity of Methanolic Extracts of Berberis aristata DC”, Hemidesmus indicus R.Br. in MCF7 Cell Line. Journal of Current Pharmaceutical Research, Vol. 1, pp. 12-15, 2010.
[29] K. V. Anis, N. V. R. Kumar, K. Ramadasan, “Inhibition of chemical carcinogenesis by berberine in rats and mice”, Journal of Pharmacy and Pharmacology, Vol. 53, Issue 5, pp. 763–68, 2001.
[30] R. S. Sharma, V. Mishra, R. Singha, N. Setha, C. R. Babua, “Antifungal activity of some Himalayan medicinal plants and cultivated ornamental species”, Fitoterapia, Vol. 79, Issue 7-8, pp. 589-91. 2008.
[31] M. Shahid, T. Rahim., A. Shahzad, A. Latif, T. Fatima, M. Rashid, A. Raza, S. Mustafa, “Ethnobotanical studies on Berberis aristata DC. Root extracts”. African Journal of Biotechnology, Vol. 8, Issue 4, pp. 556-63, 2009.
[32] M. Singha, S. Srivastava, A. Rawata, “Antimicrobial activities of Indian Berberis species” Fitoterapia, Vol. 78, Issue 7-8, pp. 574-76, 2007.
[33] R. S. Bradley, F. L. Jean, “Berberine Inhibits Intestinal Secretory Response of Vibrio cholerae and Escherichia coli Enterotoxins” Infection Immunity, Vol. 35, Issue 2, pp. 471-75, 1982.
[34] M. Romero, T. Efferth, M. A. Serrano, B. Castano, R. I. Macias, O. Briz, J. J. Marin, “Effect of artemisinin/artesunate as inhibitors of hepatitis B virus production in an "in vitro" replicative system, Antiviral Res, Vol. 68, pp. 75-83, 2005.
[35] A. Pasrija, R. Singh, S. K. Sharma, S. Singh, P. K. Bhatnagar, “Comparative Study on Antimicrobial activity of Berberis aristata from different regions and Berberine in vitro”, Flavour and Fragrance Journal, Vol. 12, Issue. 1, pp. 81-91, 2012.
[36] V. J. Padmaja, A. S. Atul, P. Krishnan, V. L. Maheshwari, “Antidiarrheal activity, chemical and toxicity profile of Berberis aristata”. Pharmaceutical Biology, Vol. 49, Issue.1, pp. 94-100, 2011.
[37] H. K. S. kumar, M. B. V. Raju, S. C. Dinda, S.K. Sahu, “Antihyperglycemic Activity of Bambusa Arundinacea”. Rasayan Journal of Chemistry, Vol. 5, No.1, pp. 112-116, 2012.
[38] N. Ahmed, M. S. A. Khan, A. M. M. Jais, N. Mohtarrudin, M. Ranjbar, M. S. Amjad, B. Nagaraju, M. Faraz, F. Pathan, A. Chincholi, “Anti-ulcer activity of Sandalwood (Santalum album L.) stem hydroalcoholic extract in three gastric-ulceration models of wistar rats”, Boletín Latino americano y del Caribe de Plantas Medicinales y Aromáticas, Vol. 12, Issue. 1, pp. 81-91, 2013.
[39] L. Jirovetz, G. Buchbauer, Z. Denkova, A. Stoyanova, I. Murgo, V. Gearon, S. Birkbeck, E. Schmidt, M. Geissler, “Comparative study on the antimicrobial activities of different sandalwood essential oils of various origin”, Flavour and Fragrance Journal, Vol. 21, pp. 465-468, 2006.
[40] S. Bakkiyaraj, S. Pandiyaraj, “Evaluation of potential antimicrobial activity of some medicinal plants against common food-borne pathogenic microorganism”, International Journal of Pharma and Bio Science, Vol. 2, Issue. 2, pp. 484-491, 2011.
[41] F. Benencia, M. C. Courreges, “Antiviral Activity of Sandalwood oil against Herpes Simplex Viruses 1& 2”, Phytomedicine , Vol. 6, Issue. 2, pp. 119-123, 1999.
[42] M. S. Khan, M. Singh, M. A. Khan, S. Ahmad, “Protective effect of Santalum album on doxorubicin induced cardiotoxicity in rats”, World Journal of Pharmaceutical Research,Vol. 3, Issue. 2, pp. 2760-2771. 2014.
[43] V. B. Desai, R. D. Hirenath, “Pharmacological Screening of HESP and Sandalwood oil”. Indian Perfumer, Vol. 35, pp. 69-70, 1991.
[44] R. Chavda, K. R. Vadalia, R. Gokani, “Hepatoprotective activity of root bark of Calatropis procera R.Br (Asclepediaceae)”, International Journal of Pharmacology, Vol. 6, Issue. 6, pp. 937-934, 2010.
[45] C. Viollon, J. P. Chaumont, “Antifungal properties of essential oils and their main components upon Cryptococcus neoformans”, Mycopathologia, pp. 128, 151-153, 1994.
[46] I. Baitar “Kitab-ul-Jamia Al Mufridaat al Advia wal Aghzia”, CCRUM, New Delhi, 1st Edition, pp. 130, 277, 1985.
[47] N. H. Ghani “Khazainul Advia”, Idara Kitabul Shifa, New Delhi, pp. 187-188, 421-422, 495, 542-43, 605-6, 682, 756-57, 869, 1097, 1231-31,1284, YNM.
[48] M. A. Hakim, “Bustanul Mufredat”, Idara Kitabus Shifa, New Delhi, pp. 60, 90, 145, 180, 209, 235-36, 249, 266, 316, 470, 558, 2002.
[49] A. H. Jurjani, “Zakhira Khawarzam Shahi”, (Urdu), Idarah Kitab Us shifa, 1st Edition, New Delhi, pp. 635-36, YNM.
[50] H. M. Kabeeruddin, “Al Qarabadeen”, CCRUM- New Delhi, pp.1212, 2006
[51] H. M. Kabeeruddin, “Sharah Asbab”, Shaukat Book Depot, Gujrat, Vol. III, pp.180-186, YNM.
[52] M. Kabeeruddin “Makhzan ul Mufredat”, Ejaz Publishing House, New Delhi, pp.108, 145, 146, 178, 212, 239, 251-52, 279, 311-13, 366, 560, 538, 574, YNM.
[53] C.P. Khare, “Indian Medicinal Plants: an illustrated dictionary”, Springer (India) Private Limited, New Delhi, pp. 150-151, 163-64, 238, 363-64, 400, 492, 491, 501, 488, 452. 652, 653, 735, 711-12, 2007.
[54] A. H. Momin, S. S. Acharya, A. V. Gajjar, “Coriandrum Sativum - Review of Advances in Phytopharmacology,” International Journal of Pharmaceutical Sciences and Research, Vol. 3, Issue. 5, pp.1233-39, 2012.
[55] H.C. Multani, “Hindustan aur Pakistan ki Jadi Bootiyan aur unke Fawaid”, Maktaba Daniyal, Lahore, pp. 19, 22, 561-63, 1006, 1009, 1009,1012, YNM.
[56] A. K. Nadkarni, “Indian Materia Medica with Ayurvedic, Unani-Tibbi, Siddha, Allopathic, Homeopathic, Naturopathic and Home remedies”, Popular Prakashan Private Ltd, Bombay: Vol. 1, pp. 140, 333, 480, 772, 873-74, 957, 965, 969-72, 991-92, 1203, 1309, 1285-86, 2009.
[57] H. M. Said, “Al Biruni’s book on Pharmacy and Materia Medica”, Hamdard National Foundation, Karachi, Pakistan, pp. 38-50, 1973.
[58] A. Safiuddin, “Unani Advia Mufreda”, Qaumi Council Barae farogh Urdu Zaban, pp. 92,153, 175, 2004.
[59] H. Teppner, “Remarks to the Onosma species O. bourgaei, O. spruneri and O. stellulata (Boraginaceae) offered, Samentauschverzeichnis, pp. 33–9, 1996.
[60] H. Reidl, R. Binzel, N. Orcan, “A new species of Onosma (Boraginaceae-Lithospermeae) from southern Turkey, Edinburgh Journal of Botany, Vol. 61, pp. 127–30, 2004.
[61] K. M. Semnani, M. Saeedi, M. Akbarzadeh, K. Moshiri, “The essential oil composition of Onosma microcarpum Dc”, Flavour Fragrance Journal, Vol. 21, pp. 314–6, 2006.
[62] T. Yokozawa, H.Y. Kim, H. J. Kim, T. Tanaka, H. Sugino, T. Okubo, D. Chu, L. R. Juneja, “Amla (Emblica officinalis Gaertn.) Attenuates Age Related Renal Dysfunction by Oxidative Stress”, Journal of Agricultural and Food Chemistry, Vol. 55, pp. 7744-52, 2007.
[63] G. Deep, M. Dhiman, A. R. Rao, R. K. Kale, “Chemopreventive potential of Triphala (a composite Indian drug) on benzo (a) pyrene induced for stomach tumorigenesis in murine tumor model system”, Journal of Experimental and Clinical Cancer Research, Vol. 24, Issue. 4, pp. 555-63, 2005.
[64] R. K. Chaudhari, “Emblica cascading antioxidant: A novel natural skin care ingredient”, Skin Pharmacology and Applied Skin Physiology, Vol. 15, Issue. 3, pp. 374-380, 2002.
[65] T. Fujii, M. Wakaizumi, T. Ikami, M. Saito, “Amla (Emblica officinalis Gaertn.) extract promotes procollagen production and inhibits matrix metalloproteinase-1 in human skin fibroblasts”, Journal of Ethno-pharmacology, pp. 53-57, 119, 2008.
[66] A. Chatterjee, S. Chattopadhyay, K. Sandip, “Biphasic Effect of Phyllanthus emblica L. Extract on NSAID-Induced Ulcer: An Anti-oxidative Trail Weaved with Immunomodulatory Effect”, Evidence-Based Complementary and Alternative Medicine, Vol. 5, Issue. 1, pp. 536-548, 2016.
[67] S. K. Bhattacharya, A. Bhattacharya, K. Sairam, S. Ghosal, “Effect of bioactive tannoid principles of Emblica officinalis on ischemia reperfusion induced oxidative stress in rat heart”, Phytomedicine, Vol. 9, Issue. 2, pp. 171-4, 2002.
[68] W. Yi-Fei, W. Ya-Fenga, W. Xiao-Yana, R. Zhea, Q. Chui-Wena, L. YiChenga, K. Kitazatoc, Qing-Duan, “Phyllaemblicin B inhibits Coxsackie virus B3 induced apoptosis and myocarditis, Antiviral Research, Issue 84, pp.150-58, 2009.
[69] J. Santoshkumar, M. S. Devarmani, M. Sajjanar, M. S. Pranavakumar, P. Dass, “A study of Anti-inflammatory activity of fruit of Emblica officinalis (Amla) in Albino rats”, Medica Innovatica, Vol. 2, Issue.1, pp. 17- 26, 2013.
[70] S. Madhuri, “Studies on estrogen induced uterine and ovarian carcinogenesis and effect of ProImmu in rat”, PhD thesis, Jabalpur, MP, RDVV, 2008.
[71] M. D. Adil, P. Kaiser, N.K. Satti, A. M. Zargar, R. A. Vishwakarma, S. A. Tasduq, “Effect of Emblica officinalis (fruit) against UVB-induced photoaging in human skin fibroblasts”, Journal of Ethnopharmacology, Vol. 132, Issue.1, pp. 109-14, 2010.
[72] K. Suresh, D. M. Vasudevan, “Augmentation of murine natural killer cell and antibody dependent cellular cytotoxicity activities by Phyllanthus emblica, a new immunomodulatory”, Journal of Ethno pharmacology, Vol. 44, Issue. 1, pp. 55-60, 1994.
[73] M. H. Mehmood, H. S. Siddiqi, A. H. Gilani, “The antidiarrheal and spasmolytic activities of Phyllanthus emblica are mediated through dual blockade of muscarinic receptors and Ca2+ channels”, Journal of Ethnopharmacology, Vol. 133, Issue. 2, pp. 856-65, 2011.
[74] S.V. Nampoothiri, A. Prathapan, O. L. Cherian, K. G. Raghu, V. V. Venugopalan, A. Sundaresan, “In vitro antioxidant and inhibitory potential of Terminalia bellerica and Emblica officinalis fruits against LDL oxidation and key enzymes linked to type 2 diabetes”, Food and Chemical Toxicology, Vol. 49, Issue. 1, pp. 125-131, 2011.
[75] B. Thaweboon, S. Thaweboon, “Effect of Phyllanthus emblica Linn. on candida adhesion to oral epithelium and denture acrylic”, Asian Pacific Journal of Tropical Medicine, Vol. 4, Issue.1, pp. 41-45, 2011.
[76] G. Liu, S. Xiong, S. Xiang, C. W. Guo, F. Ge, C. R. Yang, Y. Zhang, Y. Wang, K. Kitazato, “Antiviral activity and possible mechanisms of action of pentagalloylglucose (PGG) against influenza A virus”, Archives of Virology, Vol. 156, pp.1359-69, 2011.
[77] M, Senthil Kumar, S. Kirubanandan, R. Sripriya, P. K. Sehgal, “Triphala Promotes Healing of Infected Full-Thickness Dermal Wound”, Journal of Surgical Research, Vol. 144, Issue.1, pp. 94-101, 2008.
[78] T. Yokozawa, H. Y. Kim, H. J. Kim, T. Tanaka, H. Sugino, T. Okubo, D. Chu, L. R. Juneja, “Amla (Emblica officinalis Gaertn.) Attenuates Age Related Renal Dysfunction by Oxidative Stress”, Journal of Agricultural and Food Chemistry, Vol. 55, pp. 7744-52, 2007.
[79] R. Srirama, H. B. Deepak, U. Senthilkumar, G. Ravikanth, B. R. Gurumurthy, M. B. Shivanna, C. V. Chandrasekaran, A. Agarwal, R. U. Shaanker, “Hepatoprotective activity of Indian Phyllanthus”, Pharmaceutical Biology, Vol. 50, Issue. 8, pp. 948-53, 2012.
[80] M. Vasudevan, M. Parle, “Memory enhancing activity of Anwalachurna (Emblica officinalis Gaertn.): An Ayurvedic preparation”, Physiology & Behaviour, Vol. 91, Issue. 1, pp. 46–54, 2007.
[81] N. Kumar, W. Rungseevijitprapa, N. Narkkhong, M. Suttajit, C. Chaiyasuta, “5α-reductase inhibition and hair growth promotion of some Thai plants traditionally used for hair treatment”, Journal of Ethno pharmacology, Vol. 139, pp. 765-71, 2012.
[82] A. Sultana, K. Rahman, “Portulaca oleracea Linn. A Global Panacea with Ethno-medicinal and Pharmacological Potential”, International Journal of Pharmacy and Pharmaceutical Sciences, Vol. 5, Issue. 2, pp. 33-39, 2013.
[83] I. A. Ross, “Medicinal Plant of World”, Humana Press Inc, Totowa New Jersey, Vol. 1, Ed. 2nd, 2007.
[84] M. Mahboubi, “Rosa damascena as holy ancient herb with novel applications”, Journal of Traditional Complementary Medicine, Vol. 6, Issue. 1, 2016.
[85] T. Mahmood, H. H. Siddiqui, R. Dixit, P. Bagga, M. S. Hussain, “Protective Effect of Bombyx mori L Cocoon (Abresham) and its Formulations against Isoproterenol-Induced Cardiac Damage”, Tropical Journal of Pharmaceutical Research January; Vol. 14, Issue. 1, pp. 63-72, 2015.
[86] C. W. Seo, I. C. Um, C. W. Rico, “Antihyperlipidemic and body fat-lowering effects of silk proteins with different fibroin/sericin compositions in mice fed with high fat diet”, Journal of Agriculture Food Chemistry, Vol. 59, Issue. 8, pp. 4192 – 7, 2011.
[87] P. Promphet, S. Bunarsa, M. Sutheerawattananonda, “Immune enhancement activities of silk lutein extract from Bombyx mori cocoons”, Biological Res, Part. 15, pp. 47, 2014.
[88] R. K. Srivastav, H. H. Siddiqui, T. Mahmood, “Evaluation of cardioprotective effect of silk cocoon (Abresham) on isoprenaline-induced myocardial infarction in rats”, Avicenna Journal of Phytomedicine, Vol. 3, Issue. 3, pp. 216– 23, 2013.
[89] K. Yellamma, “Silk protein, sericin as a cognitive enhancer in Alzheimer’s disease”, Journal of Alzheimer’s disease and Parkinsonism, Vol. 4, Issue. 5, pp. 1 – 13, 2014.
[90] P. Aramwit, A. Sangcakul, “The Effect of Sericin Cream on Wound Healing in Rats”, Journal of Bioscience, Biotechnology and Biochemistry, Vol. 7, Issue. 10, pp. 2473-7, 2007.
[91] A. R. Padol, K. Jayakumar, N. B. Shridhar, “Efficacy of the silk protein based biofilms as a novel wound healing agent”, International Journal of Toxicology and Applied Pharmacology, Vol. 2, Issue. 3, pp. 31– 6, 2012.
[92] O. Amnart, D. Shimbhu, J. Tocharus, “Hypotensive and vasorelaxant effects of sericin-derived oligopeptides in rats”, ISRN Pharmacology, pp.1 – 8, 2013.
[93] W. Kaewkorn, N. Limpeanchob, W. Tiyaboonchai, “Effects of silk sericin on the proliferation and apoptosis of colon cancer cells”, Biological Research, Vol. 45, Issue. 1, pp. 45 – 50, 2012.
[94] L. YG, J. DF, L TB, “Protective effect of sericin peptide against alcohol-induced gastric injury in mice”, Chinese Medical Journal, Vol. 121, Issue. 20, pp. 2083 – 7, 2008.
[95] M. N. Padamwar, A. P. Pawar, A. V. Daithankar, “Silk sericin as a moisturizer: an in vivo study”, Journal of Cosmetic Dermatology, Vol. 4, Issue. 4, pp. 25 – 7, 2005.
[96] S. R. Niphade, M. Asad, G. K. Chandrakala, “Immunomodulatory activity of Cinnamomum zeylanicum barks”, Pharmaceutical Biology, Vol. 47, Issue 12. pp.1168 - 1173, 2009.
[97] B. Singh, “Antianxiety Investigations of Centaurea behen Linn. and Elaeocarpus ganitrus Roxb, Journal of Pharmacy Research”, Vol. 5, Issue. 3, pp. 1483-1486, 2012.
[98] C. Pushplata, “Protective effect of ethanol extract of Centaurea behen Linn. in Carbon tetra chloride- Induced Hepatitis in rats”, International Journal of Pharmacy and Parmaceutical Sciences, Vol. 6, Issue. 8, pp. 197-200, 2014.
[99] A. H. Shakeri, “Screening of several biological activities induced by different sesquiterpene lactones isolated from Centaurea behen L. and Rhaponticum repens (L.)”, Natural Products Research, Vol. 32, Issue. 12, pp.1436-1440, 2018.
[100] D. Gupta, B. Bleakley, R. K. Gupta, “Phytochemical analysis and antioxidant activity of herbal plant Doronicum hookeri”, Journal of Medicinal Plants Research, Vol. 5, Issue. 13, pp. 2736-2742, 2011.
[101] S. N. Syed, W. Rizvi, A. Kumar, A. A. Khan, S. Moin, P. A. Khan, “Study to Evaluate the Antioxidant and Hepatoprotective Activities of Roots Extracts of Doronicum hookeri in CCl4 Treated Rats”, European Journal of Medicinal Plants, Vol. 4, Issue. 6, pp. 675-685, 2014.
[102] O. P. Sharma, T. K. Bhat, “DPPH antioxidant assay revisited”, Food Chemistry, Vol. 113, pp. 1202–5, 2009.
[103] D. Manasi, K. P. Jayanta, P. P. Prasanna, “Phytochemical and antimicrobial screening of extracts of Aquilaria agallocha Roxb”, African Journal of Biotechnology, pp. 3531-3534, 2008.
[104] T. Alla, M. Handral, K. Nandakumar, N. Venkatrao, S. M. Shantakumar, “Anxiolytic and anticonvulsant activity of alcoholic extract of heartwood of Aquilaria agallocha roxb, (Thymelaeceae) in mice”, Pharmacologyonline, Vol. 1, pp. 564-572, 2007.
[105] H. Rahman, K. Vakati, M. C. Eswaraiah, A. M. Dutt, “Evaluation of hepatoprotective activity of ethanolic extract of Aquilaria agallocha leaves (EEAA) against CCl4 induced hepatic damage in rat”, Scholars Journal of Applied Medical Sciences, Vol. 1, Issue. 1, pp. 9-12, 2013.
[106] H. Hara, Y. Ise, N. Morimoto, M. Shimazawa, K. Ichihashi, M. Ohyama, M. Iinuma, “Laxative effect of agar wood leaves and its mechanism”, Scholars Journal of Applied Medical Sciences,Vol. 1, pp. 335- 345, 2008.
[107] Y. C. Kim, E. H. Lee, Y. M. Lee, K. H. Kim, B. Song, E. J. Lee, “Effect of the aqueous extract of Aquilaria agallocha stems on the immediate hypersensitivity reactions”, Journal of Ethnopharmacology, Vol. 1, pp. 31-38, 1997.
[108] S. Suebsasana, P. Pongnaratorn, J. Sattayasai, T. Arkaravichien, S. Tiamkao, C. Aromdee, “Analgesic, antipyretic, anti-inflammatory and toxic effects of andrographolide derivatives in experimental animals”, Arch Pharm Res. Vol. 32, pp.1191–200, 2009.
[109] P. B. Miniyar, H. J. Chitre, P. S. Deuskar, S. S. Karve, S. K. Jain, “Antioxidant activity of ethyl acetate extract of Aquilaria agallocha on nitrite induced methaemoglobin formation”, International Journal of Green Pharmacology,Vol. 1, pp.116-117, 2008.
[110] K. S. Bora, A. Dubey, “Evaluation of anti-anxiety activity of Melissa parviflora (Benth.) in rats”, The Thai Journal of Pharmaceutical Sciences, Vol. 39, pp. 70-75, 2015.
[111] G. Parameswari, “Note on Pharmacological Activities of Melissa officinalis L.”, Ethnobotanical Leaflets, Vol. 13, pp. 211- 12, 2009.
[112] R. H. Wolbling, K. Leonhardt, “Local therapy of herpes simplex with dried extract from Melissa officinalis, Phytomedicine, Vol. 1,pp. 25–31, 1994.
[113] G. May, G. Willuhn, “Antiviral activity of aqueous extracts from medicinal plants in tissue cultures”, Arzneimittel-Forschung, Vol. 28, pp. 1–7, 1978.
[114] H. B. Forster, H. Niklas, S. Lutz, “Antispasmodic effects of some medicinal plants”, Planta Medica, Vol. 40, pp. 309–312, 1980.
[115] M. Reiter, W. Brandt, “Relaxant effects on tracheal and ileal smooth muscles of the guinea-pig”, Arzneimittel Forschung, Vol. 35, pp. 408–414, 1985.
[116] E. Koksal, “Antioxidant activity of Melissa officinalis leaves”, Journal of Medicinal Plants Research, Vol. 5, Issue. 2, pp. 217-222, 2011.
[117] S. Kordali, A. Cakir, H. Zengin, M. E. Duru, “Antifungal activity of the leaves of three Pistacia species grown in Turkey”, Fitoterapia, Vol. 74, pp.164-167, 2003.
[118] M. S. Shtayehali, I. S. Abughdeib, “Antifungal activity of plant extract against dermatophytes”, Mycoses, Vol. 42, Issue.11-12, pp. 665-672, 1999.
[119] A. Barra, V. Goroneo, S. Dessi, P. Cabras, A. Angioni, “Characterization of the volatile constituent in the essential oil of Pistacia lentiscus l. from different origin and its antifungal and antioxidant activity”, Journal of Agriculture Food Chemistry. Vol. 55, Issue. 77, pp. 7093- 7098, 2007.
[120] K. Fillipos, K. Koliakou, K. P. Stefans, K. Jannis, C. P. Theodora, “Effect of mastic gum Pistacia lentiscus var. chia on innate cellular immune effectors”, European Journal of gastroenterology and hepatology, Vol. 21, Issue. 2, pp.143-149, 2009.
[121] A. N. Assimopoulou, S. N. Zlatanos, V. P. Papageorgeiou, “Antioxidant activity of natural resins and bioactive triterpenes in oil substrate”, Food chemistry, Vol. 92, Issue. 4, pp.721-727, 2005.
[122] S. Mansoor, A. M. Ageel, N. S. Parmar, M. Tariq, “Evaluation of mastic, a crude drug obtained from Pistacia lentiscus for gastric and duodenal anti-ulcer activity”, Journal of Ethnopharmacology, Vol. 15, Issue. 3, pp. 271-278, 1986.
[123] N. Boulebda, A. Belkhiri, F. Belfadel, A. Bensegueni, L. Bahri, “Dermal Wound Healing Effect of Pistacia lentiscus Fruit`s Fatty Oil”, Pharmacognosy Research, Vol. 1, Issue. 2, pp. 66-71, 2009.
[124] K. V. Balan, J. Prince, Z. Han, K. Dimas, M. Cladaras, J. H. Wyche, “Antiproliferative activity and induction of apoptosis in human”, Phytomedicine, Vol. 14, Issue. 4, pp. 263-72, 2007.
[125] I. Abhishek, P. Sunil, P. Hemant, B. Lindsay, “Potential Health Benefits of Indian Spices in The Symptoms of Metabolic Syndrome: A Review”, Indian Journal of Biochemistry and biophysics, Issue. 46, pp. 467- 481, 2009.
[126] R. N. Chopra, S. L. Nayar, I. C. Chopra, “Glossary of Indian Medicinal Plants”, Council of Scientific and Industrial Research (CSIR), New Delhi, 1956.
[127] Anonymous, “Standardization of single Drugs of Unani Medicine”, CCRUM, Department of AYUSH, Ministry of Health and Family Welfare, Government of India, Vol. V, pp. 53, YNM.
[128] I. Sina, “Al-Qanoon-Fit- tib (Urdu Translation by Ghulam Husain Kantoori)”, Idara kitab- Us Shifa, Delhi, Vol. 2. pp. 272- 273 (A.e), 314- 315(C.z) 328(Z.o), 333(C.s), 385 (P.l), 404(C.r), 413- 414 (N.j), 414 (C.c), 420(C.g), 426(P.n), 436(E.c), 437(S.c),439(S.l), 2007.
[129] M.A. Hakeem, “Bustan- ul- Mufradat”, Idara Taraqqi Urdu Publications, Siddiqui Book Depot, Aminabad, Lucknow, pp. 59, 121, 142, 153, 160, 185, 209, 299, YNM
[130] I. Baitar, “Al Jame- Al- Mufrada- Al Advia Wa Al- Aghzia (Urdu translation)”, CCRUM, New Delhi, Vol. II, 2000.
[131] R. N. Chopra, S. L. Nayar, I. C. Chopra, “Glossary of Indian Medicinal Plants”, Council of Scientific and Industrial Research, New Delhi, 1956.
[132] K. R. Kirtikar, B. D. Basu, “Indian Medicinal Plants”, International Book Distributors, Dehradun, India, Vol. IV, pp. 2435-2442(Z.o), 2442-2444(E.c), 2445-2447(A.g), 2462- 2463(C.s),2638-2640(C.r). 1996.
[133] I. G. Carlo, A. R. Tuberoso, P. Montoro, M. A. Fenu, “Antioxidant activity, cytotoxic activity and metabolic profiling of juices obtained from saffron (Crocus sativus L.) floral by-products”, Food Chemistry, pp. 18- 27, 2016.
Citation
Fouzia Bashir, Jamal Akhtar, Nighat Anjum, Shah Alam, Asim Ali Khan, "Dawa ul Misk Motadil Sada a Classical Unani Formulation for Khafaqān (Palpitation)," International Journal of Scientific Research in Biological Sciences, Vol.6, Issue.6, pp.13-22, 2019 -
Open Access Article
S. Jaya Durkga, D.N.P. Sudarmani, C. Sundareswari
Research Paper | Journal-Paper (IJSRBS)
Vol.6 , Issue.6 , pp.23-25, Dec-2019
CrossRef-DOI: https://doi.org/10.26438/ijsrbs/v6i6.2325
Abstract
The species of the reduviid bugs of family Reduviidae under Order Heteroptera (Insecta: Reduviidae) is not only one of the most abundant groups but also showing significant economics and high scientific value. Many reduviid species play an important role in the food chain of animals and plants, as well as the ecological balance. Population dynamics of reduviid bugs were studied during June 2018- March 2019 in semi-arid area in Sivakasi Taluk. The reduviids were randomly collected and identified some field records. A total of 11 species belonging to 5 subfamilies were identified in selected study area. During the study period maximum numbers of reduviid bugs were recorded during the November 2018 and minimum numbers of reduviid bugs were recorded during March 2019. Monthly variation in relative abundance of reduviid population also noted. Various diversity indices were recorded and correlation co-efficient studies were carried out between reduviid bug diversity and weather parameters.Key-Words / Index Term
Reduviid bugs, diversity, relative abundance, diversity indices, correlation coefficientReferences
[1] Capriles, J. M. Systematic Catalogue of the Reduviidae of the World (Insecta: Heteroptera), University of Puerto Rico, p. 694, 1990
[2] Sahayaraj, K. Reduviids and their merits in biological control. In Basic and Applied Aspects of Biopesticides, Springer India, pp. 195–214, 2014
[3] Ambrose, D. P. A checklist of Indian assassin bugs (Insecta: Hemiptera: Reduviidae) with taxonomic status, distribution and diagnostic morphological characteristics. Zoos Print Journal., 21, 2388–2406, 2006
[4] Schaefer, C. W. Reduviidae (Hemiptera: Heteroptera) as agents of biological control. Bicovas, 1, 27–33, 1988
[5] Ambrose, D. P. Biocontrol potential of assassin bugs (Hemiptera: Reduviidae). Journal of Experimental Zoology., 6, 1–44, 2003
[6] Ambrose, D.P. and D. Livingstone. Population dynamics of three reduviids from Pennisular India. Bulletin of Entomology., 19: 201-203, 1978
[7] Ravichandran, G. Biosystematics and ecophysiology of the non tibiaroliate assassin bugs (Heteroptera: Reduviidae) of southern India. Ph. D., Thesis. Bharathiar University, Coimbatore, India. 1988
[8] Truong Xuan Lam, Wanzhi Cai, Massaki Tomokuni & Tadashi Isikawa. The assassin bug subfamily Harpactorinae (Hemiptera: Reduviidae) from Vietnam: an annotated checklist of species. Zootaxa 3931(1): 101–116, 2015
[9] Riyaz. E, Mathew. P, Paulraj. G and S. Ignacimuthu. Entomophily of apple ecosystem in Kashmir Valley, India: A review. International Journal of Scientific Research in Biological Sciences, Vol.5, Issue.5, pp.155-163. 2018
Citation
S. Jaya Durkga, D.N.P. Sudarmani, C. Sundareswari, "The Effect of Weather Factors On the Population Dynamics of Reduviids (Insecta: Heteroptera: Reduviidae) From Semi-Arid Area of Sivakasi Taluk, Virudhunagar District, Tamil Nadu," International Journal of Scientific Research in Biological Sciences, Vol.6, Issue.6, pp.23-25, 2019 -
Open Access Article
Thanusree Mallakuntla Ramesh, Hanumanth Kumar Gurajala, Rupadevi Mopati, Chandrasekhar Kathera, Pramodakumari Jasti
Research Paper | Journal-Paper (IJSRBS)
Vol.6 , Issue.6 , pp.26-31, Dec-2019
CrossRef-DOI: https://doi.org/10.26438/ijsrbs/v6i6.2631
Abstract
Phytoremediative potential of Sansevieria roxburghianawas studied in association with siderophore producing bacteria Pseudomonas flourescens in synthetic medium supplemented with different concentrations of lead (40, 80, 120 and 160 mg/L)over aperiod of 30 daysalong with control.Thechlorophyll content decreasedindicatingincreased production of reactive oxygen species effecting photosynthetic activity, this was confirmed by increased malondialdehyde content. The highest concentrations of Pb 6.1 mg g-1 and 26.4 mg g–1 were accumulated in shoots and roots of S.roxburghianagrown on Pb-rich synthetic medium inoculated with Pseudomonas flourescenscompared with uninoculated plants4.2 mg g–1 and 20.23 mg g–1. In S.roxburghianabioconcentration factor (BCF) increased with increase in lead concentration (P<0.05) beforePseudomonas flourescensinoculation and after inoculation BCF showed increase upto 160mg/L and reduced upon increasing concentration of metal.Decrease in biomass with increase in Pd concentration at 40 mg and 80 mgis observed and decreased gradually. Translocation factor (TF) increased at 40 mg, 80 mg but not at 120 mg, 160 mg concentrations without Pseudomonas flourescens and is also not significant with addition of Pseudomonas at all concentrations.The tolerance index showed increase at 40,80 concentrations and low at 120,160 mg concentrations even with inoculation of Pseudomonas flourescens. From the results it is revealed that theS.roxburghianaalong with Pseudomonas flourescens can contribute for more accumulation and high degradative potential towards lead.Key-Words / Index Term
S.roxburghiana, Pseudomonas flourescens, Phytoremediation, Bioconcentration factor, Tolerance index, Translocation factorReferences
[1] Jing Yan-de, HE Zhen-li, Yang Xiao-e. “Role of soil rhizobacteria in phytoremediation of heavy metal contaminated soils”, J Zhejiang UnivSci, Vol. 8, Issue. 3, pp. 192, 2007.
[2] Glick B.R., Grichko V.P., “Amelioration of flooding stress by ACC deaminase-containing plant growth-promoting bacteria”, Plant PhysiolBiochem, Vol. 39:11, 2010.
[3] Patil BR, Mugeraya G. “Bioremediation of heavy metals and waste water treatment using leaves and latex of calotropis procera”,. Vol. 2, pp. 34-39, 2013.
[4] Miller Marvin J. “Siderophores (microbial iron chelators) and siderophore-drug conjugates (new methods for microbially selective drug delivery)”, University of Notre Dame, http://www.nd.edu/~mmiller1/page2.html. Vol. 4, pp. 62-66, 2008.
[5] Hider R.C., Kong X. "Chemistry and biology of siderophores", Nat. Prod. Rep. Vol. 27, pp. 637-657, 2010.
[6] Cornelis P., Andrews S.C. “Iron Uptake and Homeostasis in Microorganisms”, Caister Academic Press. ISBN 978-1-904455-65-3. 2010.
[7] Imsande J, “Iron, sulfur, and chlorophyll deficiencies: a need for an integrative approach in plant physiology”, Physiol Plant, Vol. 103, pp. 139, 1998.
[8] Qaiser S, Saleemi AR, Ahmad MM. “Heavy metal uptake by agro based waste materials”, Electron J Biotechnol, Vol. 10, pp. 409–416, 2007. doi: 10.2225/vol10-issue3-fulltext-12.
[9] Abdul-Sada K . H. “A resistance study of Pseudomonas aeruginosa to heavy metals”, Basrah J Vet Res, Vol. 8, pp. 52–60, 2009. doi: 10.33762/bvetr.2009.56874
[10] Trapet Pauline., Laure Avoscan., AgnèsKlinguer., StéphaniePateyron., Sylvie Citerne., Christian Chervin., Sylvie Mazurier., Philippe Lemanceau., David Wendehenne and AngéliqueBesson-Bard. “The Pseudomonas fluorescens siderophore pyoverdine weakens Arabidopsis thaliana defense in favour of growth in iron-deficient conditions”, Plant Physiol. pp.01537, 2015.
[11] Walker E. L., Connolly E. L. "Time to pump iron: iron-deficiency-signaling mechanisms of higher plants",. Current Opinion in Plant Biology, Vol. 11, pp. 530–535, 2008.
[12] Chase M.W., Reveal J.L., Fay M.F. “A subfamilial classification for the expanded asparagalean families Amaryllidaceae, Asparagaceae and Xanthorrhoeaceae”, Botanical Journal of the Linnean Society, Vol. 161, Issue. 2, pp. 132–136, 2009.
[13] Kumar G.H, Kumari J.P. “Heavy Metal Lead Influative Toxicity and Its Assessment in Phytoremediating Plants — A Review”, 2015. doi: 10.1007/s11270-015-2547-7
[14] Arnon D.I. “Copper enzymes in isolated chloroplasts, polyphenoloxidase in Beta vulgaris”, Plant Physiol, Vol. 24, pp. 1-2, 1949.
[15] Harborne JB. “Phytochemical methods, guiding the modern way to analyze plant.”, Penerbit ITB. Bandung. Indonesia. 1987.
[16] Heath R.L., Packer L. “Photoperoxidation in isolated chloroplasts.Arch. Biochem. Biophysics”, Vol. 125, pp. 189-198, 1968.
[17] Petriccione M., Di Patre D., Ferrante P., Papa S., Bartoli G., Fioretto A., Scortichini M.V. “Effects of Pseudomonas fluorescens seed bioinoculation on heavy metal accumulation for mirabilis jalapa phytoextraction in Smelter-contaminated soil”, Water Air Soil Pollut, Vol. 224, pp. 1645, 2013.
[18] Geoffrey Michael Gadd. “Biosorption: critical review of scientific rationale, environmental importance and significance for pollution treatment”, jctb, Vol. 10, Issue. 6, pp. 1002, 1999.
[19] Farinati S, Dal Corso G, Bona E, Corbella M, Lampis S, Cecconi D, Polati R, Berta G, Vallini G., Furini L. “A: Proteomic analysis of Arabidopsis halleri shoots in response to the heavy metals cadmium and zinc and rhizosphere microorganisms”, Proteomics, Vol. 9, pp. 4837, 2009.
[20] Wang, Y.T., Changsong X. “Factors affecting chromium reduction in pure cultures of Bacteria”, Water Res, Vol. 29, pp. 2467, 1995.
[21] Nichols T.D., Wolf D.C., Rogers H.B., Beyrouty C.A., Reynolds C.M. “Rhizosphere microbial populations in contaminated soil”, Water, Air and Soil Pollution, 95:165, 1997.
[22] Wiltse C.C., Rooney W.L., Chen Z., Schwab A.P., Banks M.K., “Greenhouse evaluation of agronomic and crude oil-phytoremediation potential among alfalfa genotypes", Journal of Environmental Quality, 27:169-172, 1998.
Citation
Thanusree Mallakuntla Ramesh, Hanumanth Kumar Gurajala, Rupadevi Mopati, Chandrasekhar Kathera, Pramodakumari Jasti, "Role of Pseudomonas Flourescens on Lead Phytoremediation and Recovery of Adverse Effects in Sansevieria Roxburghiana Plant under Hydroponic Studies," International Journal of Scientific Research in Biological Sciences, Vol.6, Issue.6, pp.26-31, 2019 -
Open Access Article
K. Bhavani, R. Karuppasamy
Research Paper | Journal-Paper (IJSRBS)
Vol.6 , Issue.6 , pp.32-38, Dec-2019
CrossRef-DOI: https://doi.org/10.26438/ijsrbs/v6i6.3238
Abstract
The present experiment was conducted to analyze the effect of sub-lethal concentration of 1.11mg/l of arsenic (III) oxide over long-term (15, 30, 45, 60 days) exposure on the liver of zebrafish. The arsenic (III) oxide exposed zebrafish liver showed a significant increase in arsenic bioaccumulation with the increase of exposure duration. The activities of lipid peroxidation (LPO) markers like thiobarbituric acid reactive substances (TBARS) and hydrogen peroxide (H2O2) were also significantly increased with the increase of arsenic exposure duration, while the antioxidant enzymes such as superoxide dismutase (SOD), catalase (CAT), superoxide dismutase (SOD) and reduced glutathione (GSH) activities were notably increased during the initial short term arsenic exposure (15 and/or 30 days), but later decreased significantly in the fishes that were exposed to arsenic for an extended period (45 & 60 days) when compared to normal. Further, the hepatic enzymes like alanine transaminase (ALT), aspartate transaminase (AST) and alkaline phosphatase (ALP) levels were significantly increased in serum, and degenerative changes were also found in the histology of the zebrafish liver. Thus, the above results suggest that long-term exposure to arsenic can lead to bioaccumulation of arsenic as well as alter the function and tissue architecture of the zebrafish liver.Key-Words / Index Term
Arsenic; long-term exposure; lipid peroxidation; zebrafish; liverReferences
[1] J.Y. Chung, S.D, Yu SD, Y.S. Hong, “Environmental source of arsenic exposure”, J Prev Med Public Health, Vol.47, Issue.5, pp.253–257, 2014.
[2] World health organization, 2018. Arsenic. available at: https://www.who.int/news-room/fact-sheets/detail/arsenic.
[3] J. Pei, J. Zuo, X. Wang, J. Yin, L. Liu, W. Fan, “The Bioaccumulation and Tissue Distribution of Arsenic Species in Tilapia”. Int. J. Environ. Res. Public Health. Vol.16, Issue.2, pp. 757, 2019.
[4] P. Mandal, “An insight of environmental contamination of arsenic on animal health”. Emerging Contaminants. Vol.3, Issue.1, pp.17-22, 2017.
[5] C.M. Liao, J.W. Tsai, M.P. Ling, H.M. Laing, Y.H. Chou, “Organspecific toxicokinetics and dose-response of arsenic in tilapia Oreochromis mossambicus”. Arch. Environ. Contam. Toxicol. Vol.47, pp.502-510, 2004.
[6] J. Cui, B. Wu, R.S. Halbrook, S. Zang, “Age-dependent accumulation of heavy metals in liver, kidney and lung tissues of homing pigeons in Beijing, China:, Ecotoxicology. Vol.22, Issue.10, pp.1490-1477, 2013.
[7] S. Barhoumi, I. Messaoudi, F. Gagne, A. Kerkeni, “Spatial and seasonal variability of some biomarkers in Salaria basilisca (Pisces: Blennidae): Implication for biomonitoring in Tunisian coasts”. Ecological Indicators. Vol.14, Issue.1, pp.222-228, 2012.
[8] T. Dey, K. Gogoi, B. Unni, “Role of environmental pollutants in liver physiology: special references to peoples living in the oil drilling sites of Assam”. PLoS One. Vol.10, Issue.4, pp.e0123370, 2015.
[9] S. Alarifi, D. Ali, S. Alkahtani, M.A. Siddiqui, B.A. Ali, “Arsenic trioxide-mediated oxidative stress and genotoxicity in human hepatocellular carcinoma cells”. Onco Targets Ther. Vol. 6, Issue.6, pp.75–84, 2013.
[10] Sunaina, K. Bhardwaj, A. Ansari, “Oxidative stress biomarkers in assessing arsenic tri oxide toxicity in the Zebrafish, Danio rerio”. International Journal of Fisheries and Aquatic Studies. Vol.4, Issue.7, pp.08-13, 2016.
[11] K. Bambino, C. Zhang, C. Austin, C. Amarasiriwardena, M. Arora, J. Chu, “Inorganic arsenic causes fatty liver and interacts with ethanol to cause alcoholic liver disease in zebrafish”. Dis Model Mech. Vol.11, Issue.2, 2018
[12] K. Bhavani, R. Karuppasamy, “Acute toxicity bioassay and behavioral changes on zebra fish, Danio rerio (Hamilton) Under Arsenic Trioxide”. Internatational Journao of Modern Research and Review. Vol.2, Issue.1, pp.40-46, 2014.
[13] T. Wood, M.C. Bind, A.F. Clark, “Phosphatases,antigen dependent makers of rat. Prostate”. Can.J.Biochem. Vol.54, pp.340-343, 1976.
[14] H. Ohkawa, N. Ohishi, K. Yagi, “Assay for lipid peroxidation in animal tissues by thiobarbituric acid reaction”. Ann Biochem. Vol.95, pp.351–358, 1979.
[15] P. Kakkar, B. Das, P. Viswanathan, “A modified method for assay of superoxide dismutase”. Ind J Biochem Biophys. Vol.21, pp.131–132, 1984.
[16] A.K. Sinha, “Colorimetric assay of catalase”. Anal Biochem. Vol.47, pp.389–394, 1972.
[17] J.T. Rotruck, A.l. Pope, H.E. Ganther, A.B. Swanson, D.G. Hafeman, W.G. Hoekstra, :Selenium: biochemical role as a component of glutathione peroxidase”. Science. Vol. 179, pp. 588, 1973.
[18] G. Ellman, “Tissue sulphydryl groups”. Arch Biochem Biophys. Vol.32, pp.70–77, 1959
[19] Z. Dong, C. Liu, Y. Yan, K. Semple, R. Naidu, “Using publicly available data, Physiologically-based pharmacokinetic model and Bayesian simulation to improve arsenic non-cancer dose-response”. Environ. Int. Vol.92–93, pp.239–246, 2016.
[20] J. Pei, J. Zuo, X. Wang, J. Yin, W. Fan, “The Bioaccumulation and Tissue Distribution of Arsenic Species in Tilapia”.Int. J. Environ. Res. Public Health. Vol.16, Issue.5, pp 757, 2019.
[21] Das, B.G. Unni, M. Bhattacharjee, P.K. Baruah, S. Das, S.B. Wann, “Evaluation of heavy metal exposure in oil drilling sites”. Res J Chem Environ. Vol.15, Issue.2, pp.91–94, 2011.
[22] P. Akbary, “Sartipi Yarahmadi, S. & Jahanbakhshi, A. Environ Sci Pollut Res. Vol. 25, pp.1800, 2018.
[23] Ghaffar, R. Hussain, M. Aslam , G. Abbas, A. Khan, “Arsenic and Urea in Combination Alters the Hematology, Biochemistry and Protoplasm in Exposed Rahu Fish (Labeo rohita) (Hamilton, 1822)”. Turkish Journal of Fisheries and Aquatic Sciences. Vol.16, pp.289-296, 2016.
[24] K.B. Davis, C.A. Goudie, B.A. Simco, T.R. Tiersch, G.J. Carmichael, “Influence of dihydrotestosterone on sex determination in channel catfish and blue catfish: period of developmental sensitivity”. Gen. Comp. Endocrinol. Vol.86, pp.147-151, 1992.
[25] N. Ercal, H. Gurer-Orhan, and N. Aykin-Burns, “Toxic metals and oxidative stress, Part I. Mechanisms involved in metal-induced oxidative damage”. Curr. Top. Med. Chem., Vol.1, pp.529-539, 2001.
[26] S. Nabi, S. Tanveer, S. Ahmad Ganie, “Glutathione-S-transferase, Superoxide Dismutase (GST, SOD) Levels, Protein Content and Lipid Peroxidation in Schizothorax plagiostomus under the Infection of Pomphorhynchus in Nallah Sukhnag of Kashmir Valley”. Pakistan Journal of Biological Sciences. Vol.20, pp.442-446, 2017.
[27] G.W. Winston, R.T. Di Giulio, “Prooxidant and antioxidant mechanisms in aquatic organisms”. Aquat. Toxicol. Vol.19, pp.137-161, 1991.
[28] J.A. Adeyemi, “Oxidative stress and antioxidant enzymes activities in the African catfish, Clarias gariepinus, experimentally challenged with Escherichia coli and Vibrio fischeri. Fish Physiol. Biochem. Vol.40, pp.347-354, 2014.
[29] V.I. Lushchak, “Free radicals, reactive oxygen species, oxidative stress and its classification. Chem Biol Interact. Vol. 224, pp.164–175, 2014.
[30] D. Senthamilselvan, A. Chezhian and E. Suresh, “Synergistic Effect of Nickel and Mercury on Fatty Acid Composition in the Muscle of Fish Lates calcarifer”. Journal of Fisheries and Aquatic Science. Vol.11, pp. 77-84, 2016.
[31] E.M.B, Sorenson, “Arsenic”. In: Sorenson”, E.M.B (Ed.), Metal Poisoning in Fish. CRC Press, New York, pp.61-99. 1991.
[32] S. Abarghuei, S, Hedayati, A, Ghorbani R, Kolangi H, Bagheri T, “Histopathological eوٴects of waterborne silver nanoparticles and silver salt on the gills and liver of goldfish”. Int J Environ Sci Technol. Vol.13,pp. 1753-1760, 2016.
[33] Y.J.Kim, J.M. Kim JM, “Arsenic Toxicity in Male Reproduction and Development”. Dev.Reprod. vol.19, Issue.4, pp.167–180, 2015.
[34] A.P. Thakkar, H.J. Shah, N.D. Patel, "Alteration in Antioxidant Defence System and Oxidative Stress in blood of Liver Cirrhosis", International Journal of Scientific Research in Biological Sciences, Vol.6, Issue.1, pp.47-54, 2019.
Citation
K. Bhavani, R. Karuppasamy, "Long-Term Exposure of Arsenic Caused Arsenic Bioaccumulation, Imbalance in Hepatic Markers, Oxidative Status, and Histological Changes in the Liver of Zebrafish (Danio Rerio)," International Journal of Scientific Research in Biological Sciences, Vol.6, Issue.6, pp.32-38, 2019 -
Open Access Article
Abhaykumar Kamble, Paramjyothi L Swamy
Research Paper | Journal-Paper (IJSRBS)
Vol.6 , Issue.6 , pp.39-46, Dec-2019
CrossRef-DOI: https://doi.org/10.26438/ijsrbs/v6i6.3946
Abstract
The present study reports potential activities like cytotoxic, genotoxic and apoptotic activity of phenolic compound 4-(4-(3,4-dimethoxyphenyl)hexahydrofuro[3,4-c]furan-1-yl)-2-methoxyphenyl acetate isolated from methanolic extract of Pandanus odorattissimus. The compound showed a significant cytotoxic effect on MDA-MB-231 cell line. Exposure of the compound reduced the viability of MDA-MB-231 cells after 24, 48 and 72 hours, the compound exerted a significant cytotoxic effect on MDA-MB-231 cells. The compound also induced significant DNA damage. The results of comet assay with pattern of the MDA-MB-231 cells has shown an intact head and complete absence of DNA fragments in the form of tail suggesting that the doses are not genototoxic. The phenolic compound at concentration of 20 µg/mL, showed an increase in percentage tail of DNA upto 5.87 units when compared to control 5.05.Key-Words / Index Term
Cytotoxic activity, Comet assay, Pandanus odorattissimus L, MDA-MB-231 cells.References
[1] Shahedur R, Faizus S, Asif I, BMC Complementary and Alternative Medicine, 11, 76, 2011.
[2] Weimin Z, Lili Z, Jürgen R, Pharm Biol, 9, 886, 2009.
[3] Dongwu L, Zhiwei C, J Breast Cancer, 2, 133, 2013.
[4] Schwartsmann G, Ratain MJ, Cragg GM, Wong JE, Saijo N, Parkinson DR et al. Anticancer drug discovery and development throughout the world. Journal of Clinical Oncology;20:47S–59S, 2002.
[5] Newman DJ, Cragg GM, Snader KM.Natural products as sources of new drugs over the period. J. Nat. Prod;66:1022-37, Jul 2003.
[6] 6. Srivastava SK, Rai V, Srivastava M, Ra AK, wat S, Mehrotra S. Estimation of heavy metals in different Berberis Species and its market samples. Environ Monit Assess.;116:315-20, May 2006.
[7] Gupta SC, Kim JHS, Prasad BB. Regulation of survival, proliferation, invasion, angiogenesis, and metastasis of tumor cells through modulation of inflammatory pathways by nutraceuticals, Cancer Metastasis Rev;29: 405, Sep 2010.
[8] Sun Y, Xun K, Wang Y, Chen X. A systematic review of the anticancer properties of berberine, a natural product from Chinese herbs. Anticancer Drugs;20:757-69, 2009.
[9] Keerthikar and Basu.. Indian Medicinal Plant, Sri Satguru Publication. Vol. 10 p.3565, 2000.
[10] J.paul, Cell and Tissue Culture : pp 177- 184, chruchill livingstone, Edinburgh. 1975.
[11] Mosmann, T. Rapid Colorimetric Assay for Cellular Growth and Survival: Application to Proliferation and Cytotoxicity Assays. Journal of Immunological Methods, 65, 55-63, 1983.
[12] Y.O. Son, J. Kim, J.C. Lim, Y. Chung, G.H. Chung, J.C. lee Ripe fruits of Solanum nigrum L. inhibit cell growth and induce apoptosis in MCF-7 cells Food Chem. Toxicol., 41 , pp. 1421-1428, 2003.
[13] Collins A. R., Oscoz A. A., Brunborg G., Gaivão I., Giovannelli L., Kruszewski M., et al. .. The comet assay: topical issues. Mutagenesis 23, 143–151, 2008.
[14] Singh N. P., McCoy M. T., Tice R. R., Schneider E. L.. A simple technique for quantitation of low levels of DNA damage in individual cells. Exp. Cell Res. 175, 184–191, 1988.
[15] Hartmann A., Plappert U., Raddatz K., Grünert-Fuchs M., Speit G.. Does physical activity induce DNA damage? Mutagenesis 9, 269–272, 1994.
[16] Grusch M, Fritzer-Szekeres M, Fuhrmann G, Rosenberger G, Luxbacher C, Elford HL, Smid K, Peters GJ, Szekeres T and Krupitza G (2001) Activation of caspases and induction of apoptosis by amidox and didox. Exp. Hematol. In press Stone MJ, Klintmalm GB, Polter D, et al: Neoadjuvant chemotherapy and liver transplantation for hepatocellular carcinoma: A pilot study in 20 patients. Gastroenterology;104:196–202, 1993.
[17] Fenaux P, Chomienne C, Degos L. Treatment of acute promyelocytic leukaemia. Best Pract Res Clin Haematol;14(1):153-74, 2001.
[18] Mayorga P, Perez KR, Cruz SM, Caceres A.. Comparison of bioassays using the anostracan crustaceans Artemia salina and Thamnocephalus platyurus for plant extract toxicity screening. Rev Bras Farmacogn. 20(6):897–903, 2010.
[19] T. T. Jong and S. W. Chau, “Antioxidative Activities of Constituents Isolated from Pandanus Odoratissimus,” Phytochemistry, Vol. 49, No. 7, pp. 2145-2148, 1998.
Citation
Abhaykumar Kamble, Paramjyothi L Swamy, "Cytotoxic Activity of Phenolic Compound Isolated From Pandanus Odorattissimus against (MDA-MB-231) Breast Cancer Cell Lines," International Journal of Scientific Research in Biological Sciences, Vol.6, Issue.6, pp.39-46, 2019 -
Open Access Article
Thanusree Mallakuntla Ramesh, Hanumanth Kumar Gurajala, Rupadevi Mopati, Esther Lebonah Dulla, Pramodakumari Jasti
Review Paper | Journal-Paper (IJSRBS)
Vol.6 , Issue.6 , pp.47-51, Dec-2019
CrossRef-DOI: https://doi.org/10.26438/ijsrbs/v6i6.4751
Abstract
Rhizosphere microorganisms harbour the plant accumulators and contribute to the metal extraction process. Out of bacteria and fungi, bacteria were more tolerant to heavy metals than fungi. A variety of bacteria growing in metalliferous soils helps to accumulate metals in plants in their harvestable parts and have the potential to be used for remediation of heavy metal polluted lands called plant-assisted bioremediation. The present review focuson examining the current concepts and published data on the role of rhizosphere processes, heavy metal pollution, degradation,role of rhizodeposits, plant hormones, plant secondary metabolites, siderophores and carboxylic acids and conclude with major controls that may be used for their management in plant-assisted bioremediation.Key-Words / Index Term
Rhizosphere microorganisms, metal extraction, remediation, polluted lands, bioremediationReferences
[1] Antonella Furini, Anna Manara and Giovanni Dal Corso Editorial: “Environmental phytoremediation: plants and microorganisms at work”, Vol. 6, pp. 520-521, 2014.
[2] Bruins M. R., Kapil S., Oehme F. W. “Microbial resistance to metals in the environment”, Ecotoxicology and Environmental Safety. Vol. 45, Issue. 3, pp. 198–207, 2000. doi: 10.1006/eesa.1999.1860.
[3] Selvin J., ShanmughaPriya S., SeghalKiran G., Thangavelu T., SapnaBai N. “Sponge-associated marine bacteria as indicators of heavy metal pollution”,. Microbiological Research. Vol. 164, Issue. 3, pp. 352–363, 2009. doi: 10.1016/j.micres.2007.05.005.
[4] Singh SK, Singh PP, Gupta A, et al. “Tolerance of Heavy Metal Toxicity Using PGPR Strains of Pseudomonas Species”,. In: PGPR Amelioration in Sustainable Agriculture. pp 239–252, 2012.
[5] Joner E J, Johansen A, Loibner A P, de la Cruz M A, Szolar O H, Portal J M and Leyval C. “Rhizosphere effects on microbial community structure and dissipation and toxicity of polycyclic aromatic hydrocarbons (PAHs) in spiked soil”, Environ. Sci. Technol. Vol. 35, pp. 2773–2777, 2001.
[6] Rajkumar M1, Sandhya S, Prasad MN, Freitas H. “Perspectives of plant-associated microbes in heavy metal phytoremediation”,. Biotechnol Adv. Vol. 30, Issue. 6, pp. 1562-74, 2012.
[7] Krämer, U. “Phytoremediation: novel approaches to cleaning up polluted soils”,. Curr. Opin. Plant Biol. Vol. 16, pp. 133–141, 2005. doi: 10.1016/j.copbio.2005.02.006
[8] Lee A Newman and Charles M Reynolds. “Phytodegradation of organic compounds”, Current Opinion in Biotechnology, Vol. 15, pp. 225–230, 2004.
[9] Vangronsveld, J., Herzig, R., Weyens, N., Boulet, J., Adriaensen, K., Ruttens, A., et al.. “Phytoremediation of contaminated soils and groundwater: lessons from the field”, Environ. Sci. Pollut. Res. Int. Vol. 16, pp. 765–794, 2009. doi: 10.1007/s11356- 009-0213-6
[10] Al-Gheethi AAS, Lalung J, Noman EA, et al, “Removal of heavy metals and antibiotics from treated sewage effluent by bacteria”, Clean Technol. Environ. Policy Vol. 17, pp. 2101–2123, 2015.
[11] Ma Y, Rajkumar M, Zhang C, Freitas H, “Beneficial role of bacterial endophytes in heavy metal phytoremediation”, J Environ Manage Vol. 174, pp. 14–25, 2016. doi: 10.1016/j.jenvman.2016.02.047
[12] Zhang Q, Achal V, Xiang WN, Wang D, “Identification of heavy metal resistant bacteria isolated from Yangtze river, China”, Int J Agric Biol Vol. 16, pp. 619–623, 2014.
[13] Guo QW, Wan R, Xie SG, “Simazine degradation in bioaugmented soil: urea impact and response of ammonia oxidizing bacteria and other soil bacterial communities”, Environ Sci Pollut Res Vol. 21, pp. 337–343, 2014.
[14] Lopes AR, Danko AS, Manaia CM, Nunes OC, “Molinate biodegradation in soils: natural attenuation versus bioaugmentation”, ApplMicrobiolBiotechnol Vol. 97, pp. 2691–2700, 2013.
[15] Onneby K, Jonsson A, Stenstrom J, “A new concept for reduction of diffuse contamination by simultaneous application of pesticide and pesticide-degrading microorganisms”, Biodegradation, Vol. 21, pp. 21–29, 2010.
[16] Onneby K, Hakansson S, Pizzul L, Stenstrom J, “Reduced leaching of the herbicide MCPA after bioaugmentation with a formulated and stored Sphingobium sp”, Biodegradation Vol. 25, pp. 291–300, 2014.
[17] Pimmata P, Reungsang A, Plangklang P, “Comparative bioremediation of carbofuran contaminated soil by natural attenuation, bioaugmentation and biostimulation”, Int Biodeterior Biodegrad Vol. 85, pp. 196–204, 2013.
[18] Wan R, Yang YY, Sun WM, Wang Z, Xie SG, “Simazine biodegradation and community structures of ammoniaoxidizing microorganisms in bioaugmented soil: impact of ammonia and nitrate nitrogen sources”, Environ Sci Pollut Res Vol. 21, pp. 3175–3181, 2014.
[19] Kim, Y.M., Nam, I.H., Murugesan, K.S., Crowley, D.E., Chang, Y.S., “Biodegradation of diphenyl ether and transformation of selected brominated congeners by Sphingomonas sp”, PH-07. Appl. Microbiol. Biotechnol. Vol. 77, Issue. 1, pp. 187-194, 2007.
[20] Walter W. Wenzel. “Rhizosphere processes and management in plant-assisted bioremediation (phytoremediation) of soils”, Plant Soil Vol. 5, pp. 321:385–408, 2009.
[21] Fan, S. X., Li, P. J., Gong, Z. Q., Ren, W. X., and He, N. Promotion of pyrene degradation in rhizosphere of alfalfa (Medicagosativa L.). Chemosphere, Vol. 71, pp. 1593–1598, 2008. doi: 10.1016/j.chemosphere.2007.10.068
[22] Glick, B. R. Using soil bacteria to facilitate phytoremediation. Biotechnol. Adv. Vol. 28, pp. 367–374, 2010. doi: 10.1016/j.biotechadv.2010.02.001
[23] Li, Y., Liang, F., Zhu, Y. F., and Wang, F. P. “Phytoremediation of a PCB contaminated soil by alfalfa and tall fescue single and mixed plants cultivation”, J. Soil. Sediment. Vol. 13, pp. 925–931, 2013. doi: 10.1007/s11368-012-0618-6
[24] L. Wood J, Liu W, et al, “Microorganisms in heavy metal bioremediation: strategies for applying microbial-community engineering to remediate soils”, AIMS Bioeng Vol. 3, pp. 211–229, 2016. doi: 10.3934/bioeng.2016.2.211
[25] Kannabiran K, “Actinobacteria are better bioremediating agents for removal of toxic heavy metals: An overview”, Int J Environ Technol Manag Vol, 20, pp. 129–138, 2017. doi: 10.1504/IJETM.2017.089649
[26] Cioica N, Tudora C, Iuga D, et al, “A review on phytoremediation as an ecological method for in situ clean up of heavy metals contaminated soils”, In: E3S Web of Conferences. 2019.
[27] Ranjitha J, Raj A, Kashyap R, et al, Removal of heavy metals from industrial effluent using salvinia molesta. Int J ChemTech Res Vol. 9, pp. 608–613, 2016.
[28] Chaudhry Q, Blom-Zandstra M, Gupta S, Joner EJ, "Utilising the synergy between plants and rhizosphere microorganisms to enhance breakdown of organic pollutants in the environment", Environ Sci Pollut Res Vol. 12, pp. 34–48, 2005.
[29] Melanie Kuffner &Markus Puschenreiter & Gerlinde Wieshammer & Markus Gorfer & Angela Sessitsch, "Rhizosphere bacteria affect growth and metal uptake of heavy metal accumulating willows", Plant Soil Vol. 304, pp. 35–44. 2018.
[30] Angela Sessitsch, Melanie Kuffner, Petra Kidd, Jaco Vangronsveld, Walter W. Wenzel, Katharina Fallmann,and Markus Puschenreiter."The role of plant-associated bacteria in the mobilization and phytoextraction of trace elements in contaminated soil", Soil Biol Biochem. Vol. 60, pp. 182–194, 2013.
[31] Sheng X-F, Xia J-J, " Improvement of rape (Brassica napus) plant growth and cadmium uptake by cadmium resistant bacteria", Chemosphere Vol. 64, pp. 1036–1042, 2006.
[32] Shelton, D.R., Khader, S., Karns, J.S., Pogell, B.M., "Metabolism of twelve herbicides by Streptomyces", Bio-degradation Vol. 7, pp. 129-136, 1996.
[33] Staicu, L. C., van Hullebusch, E. D., Lens, P. N. L., Pilon-Smits, E. A. H., and Oturan, M. A. "Electro coagulation of colloidal biogenic selenium", Environ. Sci. Pollut. Res. Int. Vol. 22, pp. 3127–3137, 2015. doi: 10.1007/s11356-014-3592-2
[34] Hernlem B.J., Vane L.M., Sayles G.D. "Stability constants for complexes of the siderophore desferrioxamine B with selected heavy metal cations", Inorganica Chimica Acta. Vol. 244, pp.179–184, 1996.
[35] Hider R.C., Kong X. "Chemistry and biology of siderophores", Natural Products Report. Vol. 27, pp. 637–657, 2010.
[36] Nakouti I., Hobbs G. "A new approach to studying ion uptake by actinomycetes",. Journal of Basic Microbiology. Vol. 53, Issue. 11, pp. 913–916, 2013.
[37] Ryan P.R., Delhaize E., Jones D.L. "Function and mechanism of organic anion exudation from plant roots",. Annual Review of Plant Physiology and Plant Molecular Biology. Vol. 52, pp. 527–560, 2001.
[38] Küpper H., Mijovilovich A., Meyer-Klaucke W., Kroneck P.M.H. "Tissue- and age-dependent differences in the complexation of cadmium and zinc in the cadmium/zinc hyperaccumulator Thlaspi caerulescens (Ganges ecotype) revealed by X-ray absorption spectroscopy", Plant Physiology. Vol. 134, pp. 748–757, 2004.
[39] Li W., Ye Z., Wong M. "Metal mobilization and production of short-chain organic acids by rhizosphere bacteria associated with a Cd/Zn hyperaccumulating plant, Sedum alfredii", Plant Soil. Vol. 326, pp. 453–467, 2009.Citation
Thanusree Mallakuntla Ramesh, Hanumanth Kumar Gurajala, Rupadevi Mopati, Esther Lebonah Dulla, Pramodakumari Jasti, "Influence of Rhizospheric Bacteria on Growth and Metal Uptake of Heavy Metal Accumulating Plants-A Review," International Journal of Scientific Research in Biological Sciences, Vol.6, Issue.6, pp.47-51, 2019 -
Open Access Article
Antioxidant, Cytotoxicity and Antitumor of Bergia suffruticosa (whole plant)
Yasmin Hassan Elshiekh, Mona A.M. Abdelmageed
Research Paper | Journal-Paper (IJSRBS)
Vol.6 , Issue.6 , pp.52-55, Dec-2019
Abstract
Bergia suffruticosa (Elatinaceae) is a plant that is collected from western Sudan. It is popularly used traditionally in the treatment as wounds healer and osteitis. This research aims to screen the cytotoxicity as well as antioxidants and the impact as antitumor of Bergia suffruticosa metabolites. Metabolites were extracted using different organic solvents to increasing polarity. The antioxidant was assessed using free radical scavenging activity DPPH. The petroleum ether extract was revealed the strongest antioxidant with IC50 89±0.01µg/ml, while the aqueous extract was revealed no antioxidant activity. The cytotoxicity was evaluated using the Brine shrimp lethality assay. Petroleum ether metabolites revealed high cytotoxicity with LD50 0.04ppm while the other metabolites were exhibited no cytotoxicity. The antitumor activity was assessed using SRB assay against tumor cell lines, breast carcinoma cell line (MCF7), Prostate carcinoma cell line (PC3), colon carcinoma cell line (HCT116). All metabolites were revealed activity against all cancer cells tested. The highest activity against breast cancer was exhibited by ethyl acetate with IC50 17 µg/ml. the petroleum ether extract was revealed the highest activity against prostate cancer cells with IC50 17.9 µg/ml.Key-Words / Index Term
Bergia suffruticosa; Elatinaceae; Antioxidant; Cytotoxicity; AntitumorReferences
[1] S. Pattanayak, Alternative to Antibiotics from Herbal Origin - Outline of a Comprehensive Research Project, vol. 16, no. 1. 2018.
[2] A. Barchan, M. Bakkali, A. Arakrak, R. Pagán, and A. Laglaoui, “The effects of solvents polarity on the phenolic contents and antioxidant activity of three Mentha species extracts,” Int. J. Curr. Microbiol. Appl. Sci., vol. 3, no. 11, pp. 399–412, 2014.
[3] F. Angius and A. Floris, “Liposomes and MTT cell viability assay: An incompatible affair,” Toxicol. Vitr., vol. 29, no. 2, pp. 314–319, 2015.
[4] T. O. Issa et al., “Ethnobotanical investigation on medicinal plants in Algoz area (South Kordofan), Sudan,” J. Ethnobiol. Ethnomed., vol. 14, no. 1, pp. 1–22, 2018.
[5] M. A. Mohamed, “EFFECT OF PROCESSING ON AMINO ACIDS CONTENTS OF FOUR SPECIES OF THE,” vol. 6, no. 9, pp. 3775–3780, 2015.
[6] P. Amudha, V. Vanitha, N. Pushpa Bharathi, M. Jayalakshmi, and S. Mohanasundaram, "Phytochemical analysis and invitro antioxidant screening of seagrass-Enhalus acoroides," Int. J. Res. Pharm. Sci., vol. 8, no. 2, pp. 251–258, 2017.
[7] Y. Khan and S. Nasreen, “Screening for antioxidant potential in methanolic leaf extract of Madhuca Indica L .,” vol. 2, no. 9, pp. 849–851, 2016.
[8] A. M. L. Genelyn G. Madjos1, "Comparative Cytotoxic Properties of Two Varieties of Carica papaya leaf extracts from Mindanao, the Philippines using Brine Shrimp Lethality Assay," Bull. Environ. Pharmacol. Life Sci., vol. 8, no. January, pp. 113–118, 2019.
[9] J. Mangis, T. Mansur, K. Kern, and J. Schroeder, “Selection of an Optimal Cytotoxicity Assay for Undergraduate Research.,” Bioscience J. Coll. Biol. Teach., vol. 45, no. 1, pp. 24–32, 2019.
[10] M. Vinken and V. Rogiers, "Protocols in in-vitro hepatocyte research," Protoc. Vitr. Hepatocyte Res., vol. 1250, pp. 1–390, 2015.
[11] F. Q. Alali et al., “Phytochemical studies and cytotoxicity evaluations of Colchicum tunicatum Feinbr and Colchicum hierosolymitanum Feinbr (Colchicaceae): Two native Jordanian meadow saffrons,” Nat. Prod. Res., vol. 20, no. 6, pp. 558–566, 2006.
[12] D. Jeyapragash, P. Subhashini, S. Raja, K. Abirami, and T. Thangaradjou, “Evaluation of In-vitro Antioxidant Activity of Seagrasses: Signals for Potential Alternate Source,” Free Radicals Antioxidants, vol. 6, no. 1, pp. 77–89, 2016.
[13] K. C. Chinsembu, “Plants as antimalarial agents in Sub-Saharan Africa,” Acta Trop., vol. 152, pp. 32–48, 2015.
[14] X. Xia et al., “Cellular antioxidant activity and cytotoxicity assay of canolol,” vol. 3, no. 2, pp. 111–121, 2018.
[15] P. Senthilraja and K. Kathiresan, "In vitro cytotoxicity MTT assay in Vero, HepG2, and MCF-7 cell lines study of marine yeast," J. Appl. Pharm. Sci., vol. 5, no. 3, pp. 80–84, 2015.
[16] K. Sak, T. H. Nguyen, V. D. Ho, T. T. Do, and A. Raal, “Cytotoxic effect of chamomile (Matricaria recutita) and marigold (Calendula officinalis) extracts on human melanoma SK-MEL-2 and epidermoid carcinoma KB cells,” Cogent Med., vol. 4, no. 1, pp. 1–7, 2017.
[17] W. Cordier and V. Steenkamp, “Evaluation of Four Assays to Determine Cytotoxicity of Selected Crude Medicinal Plant Extracts In vitro,” Br. J. Pharm. Res., vol. 7, no. 1, pp. 16–21, 2015.
[18] E. Of, P. Constituents, A. Property, D. N. A. Damage, I. Activity, and F. Waste, "Antioxidant Property, DNA Damage Inhibition Activity And Cytotoxicity Of Aster ( Callistephus Chinensis )," vol. 8, no. 5, pp. 977–991, 2019.
[19] S. Handali et al., “A novel 5-Fluorouracil targeted delivery to colon cancer using folic acid conjugated liposomes,” Biomed. Pharmacother., vol. 108, no. July, pp. 1259–1273, 2018.Citation
Yasmin Hassan Elshiekh, Mona A.M. Abdelmageed, "Antioxidant, Cytotoxicity and Antitumor of Bergia suffruticosa (whole plant)," International Journal of Scientific Research in Biological Sciences, Vol.6, Issue.6, pp.52-55, 2019 -
Open Access Article
B. Kamatchi Kala, R. Esakiammal Alias Eswari
Research Paper | Journal-Paper (IJSRBS)
Vol.6 , Issue.6 , pp.56-60, Dec-2019
Abstract
Improving seed germination can result in increased crop production. Various methods have been used and formulated to increase seed germination and growing efficiency of agricultural crops. Seed priming is one of the successful technologies to maximise the natural potential of seeds in the field. In the present study, growth parameters and nutrient contents were studied in the seeds of three different leafy vegetables such as Amaranthus gangeticus, Hibiscus sabdariffa and Trigonella foenum - graecum primed with 1% solution of Panchagavya at different time intervals. The results showed that seed priming with Panchagavya had a significant effect on seed germination, seedling growth and nutrient contents of all the three selected leafy vegetables.Key-Words / Index Term
Germination, Leafy vegetables, Panchagavya, Seedling growth, Seed primingReferences
[1].Noor-un-Nisamemon,Moulabuxgandahi, Vajantimalapahoja and Nasimshar, “Response of seed priming with boron on germination and seedling sprouts of broccoli”, International journal Agricultural science, Vol.3, Issue,2, pp.183-194, 2013.
[2].Soubhagya Behera, “A study on effect of hormonal priming (ga3) on seed quality parameters of solanaceous vegetables”, International journal of agricultural science and research, Vol.6, Issue.3, pp. 337-348, 2016.
[3].P.Pandey, K. Bhanuprakash, Umesh, “Effect of seed priming on seed germination and vigour in fresh and aged seeds of cucumber”, International journal of Environment, Agricultrue and biotechnology, Vol.2, Issue, 4, pp. 2261-2264, 2017.
[4].S.Sarkar, S.S. Kundu, D. Ghorai, “Validation of ancient liquid organics Panchagavya and Kunapajala as plant growth promotion”, Indian Journal traditional knowledge, Vol.13, Issue.2, pp.398-403, 2014.
[5].N. Gore, N. Sreenivasa, “Influence of liquid organic manures on growth, nutrients, contents and yield of tomato”, Journal of Agricultrual science, Vol.24,Issue.2, pp.131-157, 2011.
[6].S.AIsmail. The Earthworm Book. Other India Press, Apusa, Goa, 2005.
[7].A,AAbdul-Baki, J.D.Anderson, “Vigour determination in soybean seed by multiple criteria”. Crop Science, Vol.13,pp.630-633, 1973.
[8] Z.H.Hseu, “Evoluating heavy metal contents in nine composts using four digestion methods”, Bioresource Technology, Vol.95, pp. 53-59, 2004..
[9].APHA, Standard methods for the examination for water and waste water. 19th ed. Byrd prepass Springerfield, Washington, 1995.
[10]. C.H.Fiske, Y.SubbaRow, “The Colorimetric Determination of Phosphorus”. Journal of Biological Chemistry, Vol.66, pp. 375–400, 1925.
[11]. S.Benaseer, A. Ahamed, A. Sabir, K.Sujatha, “Effect of biopriming on seed quality parameters of blackgram (Vigna mungo L.Hepper.) seed), Agricultrure update, Vol.12, pp. 1794-1799,2017.
[12].A.D.Sharma, S.V.S.Rathore, K.Srinivasan, R.Tyagi, Comparision of various seed priming methods for seed germination, seedling vigour and fruit yield in okra (Abelmoschus esculentus L. Moench). Scientia Horticulturae, Vol.165, pp.75-81, 2014.
[13]..Dhasarathan, S. Charumathi, R.Nagavasuda, K.Cholapandian, A.J.A Ranjit singh, Plant growth promotion using Panchagavya, International journal of research and review, Vol.5, Issue,10, pp194-195, 2018.
[14].B.Tagore, Abdul Shankar, Shah Teresa, Effect of organic seed priming with cow urine at different concentrations, Advanced Journal of Agricultural Research, Vol.4,Issue.9, pp.168-171, 2017.
[15]. N.M. Shakuntala, S.N.Vasudevn, S. B. Patil, S. R. Doddagoudar, R.C.Mathad, A.G. Vijaykumar, “Organic biopriming on seed vigour inducing enzyme in paddy - an alternative to inorganics”. The Ecoscan. Special Issue.1, pp.251-25, 2012.
[16].K,Maroufi, H.A, Farahani, Increasing of germination percentage by hydropeiming method in soybean (Glycine max L.). Advances in Environmental Biology, Vol.5, Issue.7, pp.1663-1667, 2011.
[17]. J.S.Yousaf, B.Muhammad, A.Jahan and Arif, “Seed priming improves salinity tolerance of wheat varities”, Pakistan Journal of Botany, Vol.43, Issue.6 pp.2683-2686, 2011.
[18].M.Saritha, B.Vijayakumar, H.R, Yadav, L.S.Kandari, “Influences of selected organic manures on the seed germination and Seedling growth of cluster bean (Cyamopsis tetragonoloba (L.) Taub)” Scientific Technology and arts Research Journal, Vol. 2 Issue.2 pp.16-21, 2013.
[19]. H.Papen, A. Gables, E. Zumbusch, H.Rennenberg, “Chemo litho autotrophic nitrifies in the phyllosphere of a spruce ecosystem receiving high nitrogen input”. Current Microbiology, Vol.44, pp. 56-60, 2002.
[20]. M.N.Ali, Sustainable agriculture with low cost technologies, School of Agriculture and Rural development Ramakrishna mission Vivekananda university, Belur, Math, West Bengal, PP.47,2011.
Citation
B. Kamatchi Kala, R. Esakiammal Alias Eswari, "Effect of Panchagavya on Seed Germination, Seedling Growth and Nutrient Content of Some Leafy Vegetables," International Journal of Scientific Research in Biological Sciences, Vol.6, Issue.6, pp.56-60, 2019 -
Open Access Article
Epidemiology of Bipolar Disorder
T. Lokeshu, V. Jaya Kumari, V. Lakshmi, S. Radha Rani
Research Paper | Journal-Paper (IJSRBS)
Vol.6 , Issue.6 , pp.61-63, Dec-2019
Abstract
Bipolar disorder (BD) is a complex psychiatric mood disorder associated with swinging episodes of mania and depression. Lifetime prevalence of BD is 1% and bipolar spectrum disorder is 2.4%. BD is associated with high rate of premature mortality. Suicidal deaths are familiar in BD compared to general population. Early recognition helps in better treatment of the disorder so as to protect the individual from suicidal thoughts and also from socioeconomic burden.In the present study, epidemiological data was collected from Government Hospital for Mental Care, Visakhapatnam. Most of the patients who attended the hospital belonged to coastal districts of Andhra Pradesh. Of all the mental disorders diagnosed in the hospital, during the period January, 2014 to December, 2018, schizophrenia ranks first with highest number of cases. Regarding BD, more number of males were affected when compared to females. Highest prevalence was observed in 21 -30 years age group. Mania was the most common episode in both the sexes compared to depression.Key-Words / Index Term
Bipolar Disorder, Schizophrenia, Depression, ManiaReferences
[1] Craddock & L. Forty, “Genetics of affective (mood) disorders”, European Journal of Human Genetics, Vol. 14, issue.6, pp. 660-668, 2006.
[2] World Health Organization, World Mental Health Survey Consortium: prevalence, severity and unmet need for treatment of mental disorders in WHO world mental health surveys. JAMA, June 2, 291(21), pp 2581–90, 2004.
[3] Ronald C. Kessler, Patricia Berglund, Olga Demler, Robert Jin, MA; Kathleen R. Merikangas, Ellen E. Walters ,”Lifetime Prevalence and Age-of-Onset Distributions of DSM-IV Disorders in the National Comorbidity Survey Replication”, Arch Gen Psychiatry, Vol.62, pp. 593-602, June 2005.
[4] G Gururaj, N Girish , M.K. Isaac , “ Mental, Neurological and substance abuse disorders: Strategies towards a systems approach, Burden of Disease in India, NCMH Background Papers,September 2005.
[5] L. Fajutrao, J. Locklear, J. Priaulx, & A. Heyes, “A systematic review of the evidence of the burden of bipolar disorder in Europe” , Clinical Practice and Epidemiology in Mental Health,Vol. 5, issue.3, 2009.
[6] K. R Merikangas, R.Jin, J. P.He, R. C. Kessler, S.Lee, N. A.Sampson, Z. Zarkov, “Prevalence and correlates of bipolar spectrum disorder in the world mental health survey initiative”. Arch Gen Psychiatry, Vol. 68, issue.3, pp. 241-251, 2011.
[7] J. Angst, “The emerging epidemiology of hypomania and bipolar II disorder”, Journal of Affective Disorders, Vol.50, issue. 2-3, pp. 143-151, 1998.
[8] P. Bebbington & R Ramana, “The epidemiology of bipolar affective disorder”, Social psychiatry and psychiatric epidemiology, Vol.30, issue.6, pp. 279-292.1995.
[9] B. F. Grant, F. S Stinson, D. S Hasin, D. A Dawson, S. P Chou, W. J Ruan, & B Huang, “Prevalence, correlates, and comorbidity of bipolar I disorder and axis I and II disorders: results from the National Epidemiologic Survey on Alcohol and Related Conditions”, Journal of Clinical Psychiatry, Vol. 66, issue.10, pp. 1205-1215, 2005.
[10] J. H. Gold, “Gender differences in psychiatric illness and treatments: a critical review”, The Journal of Nervous & Mental Disease, Vol. 186, issue.12, pp.769-775. 1998.
[11] W Maier, B.Hofgen, A. Zobel, & M. Rietschel, “Genetic models of schizophrenia and bipolar disorder: overlapping inheritance or discrete genotypes?” European Archives of Psychiatry and Clinical Neuroscience, Vol. 255, issue.3, pp. 159-166, 2005.
[12] S Parial,” Bipolar disorder in women”, Indian journal of psychiatry, Vol.57,Suppl. 2, pp. S252-S263, 2015.
[13] R. S. Murthy, “National Mental Health Survey of India 2015-2016 “ Indian journal of psychiatry, Vol.59, issue.1, pp. 21-26, 2017.
[14] C. J. Murray, & A. D. Lopez, “Global mortality, disability, and the contribution of risk factors: Global Burden of Disease Study”, Lancet, Vol. 349, issue. 9063, pp.1436-1442, 1997.
[15] R.M. Hirschfeld, &, L. A Vornik, “Bipolar disorder--costs and comorbidity”. The American Journal of Managed Care, Vol.11, Suppl.3, pp. S85-90, 2005.
[16] B Roshanaei-Moghaddam, W Katon, “Premature mortality from general medical illnesses among persons with bipolar disorder: a review”, Psychiatr Services, Vol. 60, No.2: pp. 147-156, 2009.
[17] C. Crump, K. Sundquist, M. A. Winkleby & J. Sundquist, “Comorbidities and mortality in bipolar disorder: a Swedish national cohort study”, JAMA Psychiatry, Vol.70, issue.9, pp. 931-939, 2013.
[18] R.M. Hirschfeld , JR Calabrese , MM Weissman, M. Reed, MA. Davies , MA. Frye , PE. Keck Jr, L. Lewis , SL.McElroy , JP McNulty, KD Wagner, “Screening for bipolar disorder in the community.Journal of Clinical Psychiatry”, Jan vol.64, issue.1, pp. 53-59,2003.
[19] J. C .Robb, L. T.Young, R. G. Cooke, & R. T. Joffe, “Gender differences in patients with bipolar disorder influence outcome in the medical outcomes survey (SF-20) subscale scores.” Journal of Affective Disorders, Vol.49, issue. 3, pp. 189-193,1998.
[20] I. Kawa, J. D.Carter, P. R., Joyce, C. J.Doughty, C. M.Frampton, J. E .Wells, R. J Olds, “Gender differences in bipolar disorder: age of onset, course, comorbidity, and symptom presentation”, Bipolar Disorder,Vol. 7,issue.2, pp.119-125, 2005.
[21] A. Diflorio, I. Jones, “Is sex important? Gender differences in bipolar disorder”,International Review of Psychiatry, vol.22, issue.5, pp. 437-52, 2010.
[22] L. Miguel ,C. Roncero , C López-Ortiz , M Casas, “Epidemiological and diagnostic axis I gender differences in dual diagnosis patients” Adicciones Vol.23, issue.2, pp.165-172, 2011.
[23] Saioa López-Zurbano & Ana González-Pinto,“Gender Differences in Bipolar Disorder, ,Psychopathology in women, Springer International Publishing Switzerland, September, pp 641-659, 2015.
[24] Trisha Suppes,” Gender Differences in Bipolar Disorder, CNS Spectrums’’, Volume 11, Issue S5, pp. 2-4, May,2006.Citation
T. Lokeshu, V. Jaya Kumari, V. Lakshmi, S. Radha Rani, "Epidemiology of Bipolar Disorder," International Journal of Scientific Research in Biological Sciences, Vol.6, Issue.6, pp.61-63, 2019
Next Last |
You do not have rights to view the full text article.
Please contact administration for subscription to Journal or individual article.
Mail us at support@isroset.org or view contact page for more details.